Changes

Jump to navigation Jump to search
no edit summary
Line 1: Line 1: −
      
===1. [[Rheumatoid Arthritis]]===
 
===1. [[Rheumatoid Arthritis]]===
   −
===2. Diabetes Mellitus type I===
+
===2.  
[[Image:Diabetes Mellitus Type IV hypersensitivity.jpg|right|thumb|150px|Diabetes Mellitus-Brian Catchpole RVC 2008]]
  −
 
  −
'''Pathogenesis:'''
  −
 
  −
* [[Type IV Hypersensitivity - WikiBlood|Type IV hypersensitivity]]
  −
* The CTLs think that all the beta cells in the pancreas are infected by a virus, as it wrongly detects a self antigen presented by the MHC class I on the surface of the cell as foreign.
  −
* Autoreactive CD8+ CTLs are inadvertently activated, destroying the beta cells, thus preventing the secretion of insulin and causing diabetes type 1 (see diagram).
  −
 
  −
[[Category:Cell Mediated Autoimmune Diseases]][[Category:To Do - Blood]]
   
===3. Hypothyroidism (lymphocytic throiditis)===
 
===3. Hypothyroidism (lymphocytic throiditis)===
  
Author, Donkey, Bureaucrats, Administrators
53,803

edits

Navigation menu