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==Description==
==Description==
Lymphoma is caused by malignant clonal expansion of lymphoid cells and most commonly arises from lymphoid tisses including the bone marrow, thymus, lymph nodes and spleen. Lymphoma is documented to be the most common haematopoietic neoplasm in dogs.
Lymphoma is caused by malignant clonal expansion of lymphoid cells and most commonly arises from lymphoid tisses including the bone marrow, thymus, lymph nodes and spleen. Lymphoma is documented to be the most common haematopoietic neoplasm in dogs. Certain varieties of lymphoma in cats is associated with FeLV and FIV.
In the dog, multicentric lymphoma is most common representing 80% of cases. Alimentary, cutaneous, mediastinal and extranodal sites are less common. Additionally the majority of lymphoma cases in dogs are of the B-cell immunophenotype.
In cats
* Localised lymphoma: can be intramural or extend intraluminally. The lesion may be focal or multifocal. The tumour can be of a variety of shapes namely nodular, plaque-like or circumferential. Circumferential transmural or intramural tumours often bulge outward since the diseased muscle atrophies so that rows of lymphocytes remain supported by parallel bands of reticulum fibers only. The circumferential intramural form is the most frequently seen in the feline intestine.
* Localised lymphoma: can be intramural or extend intraluminally. The lesion may be focal or multifocal. The tumour can be of a variety of shapes namely nodular, plaque-like or circumferential. Circumferential transmural or intramural tumours often bulge outward since the diseased muscle atrophies so that rows of lymphocytes remain supported by parallel bands of reticulum fibers only. The circumferential intramural form is the most frequently seen in the feline intestine.
* Diffuse lymphoma: with these tumours there is a granular or cobblestone appearance to the mucosa. The mesenteric lymph nodes are often affected.
* Diffuse lymphoma: with these tumours there is a granular or cobblestone appearance to the mucosa. The mesenteric lymph nodes are often affected.