Difference between revisions of "Bullous Pemphigoid"
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| Line 13: | Line 13: | ||
| + | [[Category:Type II Hypersensitivity Diseases]] | ||
[[Category:Integumentary System - Autoimmune Reactions]] | [[Category:Integumentary System - Autoimmune Reactions]] | ||
[[Category:Antibody Mediated Autoimmune Diseases]] | [[Category:Antibody Mediated Autoimmune Diseases]] | ||
[[Category:To Do - Blood]][[Category:To Do - Clinical]] | [[Category:To Do - Blood]][[Category:To Do - Clinical]] | ||
Revision as of 17:01, 22 February 2011
Pathogenesis: Type II hypersensitivity?
- Dogs and horses
- Involves oral cavity, mucocutaneous junctions, groin and axilla
- Subepidermal vesicles and bullae
- Antibodies bound to basement membrane
- Grossly:
- Similar to Pemphigus vulgaris
- Microscopically:
- Bullae containing fibrin, neutrophils or eosinophils
- Basement membrane forms floor of bullae and roof is lined with basal cells
- Bullae may rupture -> ulcers