Difference between revisions of "Canine Dermatomyositis"
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(Created page with " *Affects puppies of collies and shetland sheepdogs from 8 weeks of age *Lesions - vesiculating dermatitis **Face, lips, external ears, later distal extremities *Microscopically:...") |
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*Affects puppies of collies and shetland sheepdogs from 8 weeks of age | *Affects puppies of collies and shetland sheepdogs from 8 weeks of age | ||
*Lesions - vesiculating dermatitis | *Lesions - vesiculating dermatitis | ||
**Face, lips, external ears, later distal extremities | **Face, lips, external ears, later distal extremities | ||
*Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring | *Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring | ||
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| + | *Hereditary in Collies and Shetland sheepdgs | ||
| + | *Lesions resemble [[Muscles Inflammatory - Pathology#Canine polymyositis|canine polymyositis]] | ||
| + | *Also degeneration of blood vessels -> muscle [[Muscles Degenerative - Pathology#Ischaemia|microinfarcts]] | ||
| + | *Usually generalised but temporalis and other masticatory muscles may be involved the most | ||
| + | *Microscopically: inclusion bodies in endothelial cells | ||
| + | *Best place for biopsy is anterior and most superficial temporalis muscle | ||
| + | *Also involves skin, may involve the oesophagus | ||
| + | |||
[[Category:Integumentary System - Autoimmune Reactions]] | [[Category:Integumentary System - Autoimmune Reactions]] | ||
Revision as of 16:53, 22 February 2011
- Affects puppies of collies and shetland sheepdogs from 8 weeks of age
- Lesions - vesiculating dermatitis
- Face, lips, external ears, later distal extremities
- Microscopically: interface dermatitis and basal cell degeneration of epidermis and follicular wall, atrophy of follicles, epidermal vesicles and pustules, dermal scarring
- Hereditary in Collies and Shetland sheepdgs
- Lesions resemble canine polymyositis
- Also degeneration of blood vessels -> muscle microinfarcts
- Usually generalised but temporalis and other masticatory muscles may be involved the most
- Microscopically: inclusion bodies in endothelial cells
- Best place for biopsy is anterior and most superficial temporalis muscle
- Also involves skin, may involve the oesophagus