Difference between revisions of "Calcium Hydroxylapatite Deposition Disease"

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(Created page with "*Gt Dane puppies with paraplegia *Calcium phosphate depositon has been reported in multiple diarthrodial joints of the axial and appendicular skeleton *[[More on Calcium hydroxy...")
 
 
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*Gt Dane puppies with paraplegia  
 
*Gt Dane puppies with paraplegia  
 
*Calcium phosphate depositon has been reported in multiple diarthrodial joints of the axial and appendicular skeleton
 
*Calcium phosphate depositon has been reported in multiple diarthrodial joints of the axial and appendicular skeleton
*[[More on Calcium hydroxylapatite deposition disease|More about Calcium hydroxylapatite deposition disease]]
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More about Calcium hydroxylapatite deposition disease:
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'''[Calcium hydroxylapatite deposition disease in a Great Dane puppy. Wunschmann A. et al. Vet Path (2000) 37 346-9]'''
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*This case
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**Calcium hydroxyapatite deposition in the axial skeleton and included marked fibrocartilagenous proliferation resulting in compression of the cervical cord
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**10wk old Gt Dane
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**Ca2+ and Phosphorous serum levels normal
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**May get skeletal malformations secondary  to the deposition of the mineral in the joint (starts on the articular facets of cervical vertebrae)
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**In humans, associated with point mutation in type II procollagen gene
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**?Underlying cause
  
 
[[Category:Bones - Degenerative Pathology]]
 
[[Category:Bones - Degenerative Pathology]]

Latest revision as of 12:00, 3 March 2011

  • Gt Dane puppies with paraplegia
  • Calcium phosphate depositon has been reported in multiple diarthrodial joints of the axial and appendicular skeleton


More about Calcium hydroxylapatite deposition disease:

[Calcium hydroxylapatite deposition disease in a Great Dane puppy. Wunschmann A. et al. Vet Path (2000) 37 346-9]

  • This case
    • Calcium hydroxyapatite deposition in the axial skeleton and included marked fibrocartilagenous proliferation resulting in compression of the cervical cord
    • 10wk old Gt Dane
    • Ca2+ and Phosphorous serum levels normal
    • May get skeletal malformations secondary to the deposition of the mineral in the joint (starts on the articular facets of cervical vertebrae)
    • In humans, associated with point mutation in type II procollagen gene
    • ?Underlying cause