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| *The spindle cells have granular, evenly distributed chromatin and the nuclei contain one to several small but distinct nucleoli. | | *The spindle cells have granular, evenly distributed chromatin and the nuclei contain one to several small but distinct nucleoli. |
| *The cytoplasm is wispy and often has bipolar extensions. | | *The cytoplasm is wispy and often has bipolar extensions. |
− | |l1= | + | |l1=Spindle Cell Tumours#Diagnosis |
| |q2=What is your interpretation of these findings? | | |q2=What is your interpretation of these findings? |
| |a2= | | |a2= |
| The cytological features are consistent with moderate to marked pyogranulomatous inflammation with spindle cell proliferation, most likely fibroplasia. | | The cytological features are consistent with moderate to marked pyogranulomatous inflammation with spindle cell proliferation, most likely fibroplasia. |
− | |l2= | + | |l2=Spindle Cell Tumours |
| |q3=What comments do you have regarding these findings? | | |q3=What comments do you have regarding these findings? |
| |a3= | | |a3= |
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| However, in some cases, spindle cell proliferations may be difficult to differentiate and it may be difficult or impossible to separate fibroplasia from an actively growing benign tumour or a malignant one. <br><br> | | However, in some cases, spindle cell proliferations may be difficult to differentiate and it may be difficult or impossible to separate fibroplasia from an actively growing benign tumour or a malignant one. <br><br> |
| Cellularity, degree of atypia and other concurrent features all have to be considered. In some cases, cytological evaluation can help separate these conditions with a high degree of confidence.<br><br> | | Cellularity, degree of atypia and other concurrent features all have to be considered. In some cases, cytological evaluation can help separate these conditions with a high degree of confidence.<br><br> |
− | In others the differential diagnoses cannot be differentiated on the basis of cytology alone and a biopsy will be needed to determine the definitive diagnosis.
| + | In others the differential diagnoses cannot be differentiated on the basis of cytology alone and a biopsy will be needed to determine the definitive diagnosis. |
− | |l3= | + | |l3=Spindle Cell Tumours |
| </FlashCard> | | </FlashCard> |
| | | |