Difference between revisions of "Labrador cross with mass on antebrachium"
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choice4="Bone marrow biopsy for staging purposes " | choice4="Bone marrow biopsy for staging purposes " | ||
choice5="Palpation of regional lymph node and FNA of this lymph node if enlarged." | choice5="Palpation of regional lymph node and FNA of this lymph node if enlarged." | ||
− | correctchoice="2 | + | correctchoice="2" |
feedback1="'''Incorrect'''. Although this is reasonable to check for intercurrent disease, it is unlikely that a grade 2 STS would metastasize to intra-abdominal organs so not your next choice. This option is more appropriate for high-grade or anaplastic STS." | feedback1="'''Incorrect'''. Although this is reasonable to check for intercurrent disease, it is unlikely that a grade 2 STS would metastasize to intra-abdominal organs so not your next choice. This option is more appropriate for high-grade or anaplastic STS." | ||
feedback2="'''Correct'''. This is the commonest site for metastatic disease for STS. However, you should also assess your regional lymph nodes, as in option e." | feedback2="'''Correct'''. This is the commonest site for metastatic disease for STS. However, you should also assess your regional lymph nodes, as in option e." |
Revision as of 18:36, 28 September 2012
Signalment:
- 7-year-old male neutered Labrador cross
Presenting sign:
- 7 x 5 cm firm mobile mass on the caudal aspect of the proximal antebrachium, which has grown over the past three months. Otherwise clinically well, with no evidence of lameness and no other history of illness. Physical exam is otherwise within normal limits.
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What would be your next step? |
Histopathology report |
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Gross pathology One pot is submitted:biopsy of the leg. A pece of pale tan resilient tissue measuring 7 x 5 x 5 mm. A representative section is placed in Cassette A. Histopathology This is a section of a tumour composed of sheets of neoplastic pleomorphic polyhedral to spindle cells with a mitotic index approximating 1-2 mitoses per high power field. They are accompanied by minimal collagen. The neoplastic cells have mild karyomegaly and nucleolar prominence together with abundant eosinophilic, vacuolated cytoplasm. Diagnosis Cutaneous soft-tissue sarcoma, grade 2. Comments This diagnosis is in keeping with the previous cytological findings. The minimal collagen and cytoplasmic vacuolation evident in this case raises the possibility of liposarcoma as a more specific diagnosis. In any case, this tumour is likely to be characterized by infiltrative local growth but negligible tendency for metastatic spread. |
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Review the histopathology report. What do you understand about the behaviour of soft-tissue sarcomas (STS)? |
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What is the metastatic rate of grade 2 STS? |
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What is the metastatic rate of grade 1 STS? |
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What is the metastatic rate of grade 3 STS? |
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What would you choose to do next? |
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