Difference between revisions of "Transgenic Animals - Anatomy & Physiology"

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<big><center>[[Reproductive_System#Reproductive_Technologies|'''BACK TO REPRODUCTIVE TECHNOLOGIES''']]</center></big>
 
<big><center>[[Reproductive_System#Reproductive_Technologies|'''BACK TO REPRODUCTIVE TECHNOLOGIES''']]</center></big>
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* Many mouse transgenics have been created to serve as models for human genetic diseases.
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* Less successful in other species, but goats have been created that secrete human factor VIII in their milk.
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** Cheap treatment for bleeding disorders with little risk of disease transfer.
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* Area of much future development.
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* Injection of specific gene constructs into the newly fertilized oocyte, so that they become part of the dividing cell.  Thus they are encorporated and expressed in the individual.
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* Constructs may be from the same or different species as the oocyte.

Revision as of 11:00, 17 July 2008

BACK TO REPRODUCTIVE SYSTEM
BACK TO REPRODUCTIVE TECHNOLOGIES


  • Many mouse transgenics have been created to serve as models for human genetic diseases.
  • Less successful in other species, but goats have been created that secrete human factor VIII in their milk.
    • Cheap treatment for bleeding disorders with little risk of disease transfer.
  • Area of much future development.
  • Injection of specific gene constructs into the newly fertilized oocyte, so that they become part of the dividing cell. Thus they are encorporated and expressed in the individual.
  • Constructs may be from the same or different species as the oocyte.