Difference between revisions of "Vaccines"
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<big><center>[[Host invasion by microorganisms - WikiBlood|'''BACK TO HOST INVASION BY MICROORGANISMS''']]</center></big> | <big><center>[[Host invasion by microorganisms - WikiBlood|'''BACK TO HOST INVASION BY MICROORGANISMS''']]</center></big> | ||
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Revision as of 16:02, 25 August 2008
Why Vaccinate?
- To protect against infectious diseases
- Where there is no effective treatment once infected
- E.g. FeLV, FIV
- Where disease is life-threatening
- E.g. Canine Parvovirus
- To prevent the spread of disease
- E.g. Rabies, FMDV
How do we vaccinate?
- Usually by subcutaneous injection for systemic protection (IgG)
- For mucosal immune reponse, intranasal administration is best (IgA)
What do we vaccinate with?
Passive immunisation
- Administer antibodies
- Maternally-derived antibodies in colostrum
- Antiserum (artificial)
- Immediate protection
- Short duration of action
Active immunisation
- Administer antigen so the patient's own antibodies protect against disease
- Living organisms
- Dead organisms
- Toxoids
- Subunit antigens
- DNA
- Delay in protection
- Often needs two or more doses
- Long duration of action