Difference between revisions of "Innate Immunity Flashcards"
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|linkpage =Innate Immune System - WikiBlood | |linkpage =Innate Immune System - WikiBlood | ||
|linktext =INNATE IMMUNE SYSTEM | |linktext =INNATE IMMUNE SYSTEM | ||
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|pagetype =Blood | |pagetype =Blood | ||
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| − | + | ===Actions and Tools of the Innate Immune System=== | |
| − | == | + | <FlashCard questions="14"> |
| − | + | |q1=True or False: The innate immune system responds quicker to infection than the adaptive immune system | |
| − | + | |a1=True | |
| − | + | |l1=Innate Immune System - WikiBlood#Introduction | |
| − | + | |q2=Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells? | |
| − | |- | + | |a2= |
| − | | | + | *Lipopolysaccharides or Gram Negative bacteria |
| − | + | *Peptidoglycans of gram-positive bacteria | |
| − | * | + | *Mannose sugars |
| − | | | + | *D-isoform amino acids |
| − | | | + | |l2=Innate Immune System - WikiBlood#Recognition of Microorganisms |
| − | | | + | |q3=What recognises PAMPs? |
| − | || | + | |a3=Pattern recognition receptors (PRRs) |
| − | + | |l3=Innate Immune System - WikiBlood#Recognition of Microorganisms | |
| − | + | |q4=Where in the cell are Toll-Like Receptors (TLRs) located? | |
| − | + | |a4=Cell membrane | |
| − | + | |l4=Innate Immune System - WikiBlood#Recognition of Microorganisms | |
| − | + | |q5=Where in the cell are NOD2 receptors located? | |
| − | |- | + | |a5=Cell cytoplasm |
| − | | | + | |l5=Innate Immune System - WikiBlood#Recognition of Microorganisms |
| − | | | + | |q6=Which catabolic enzymes digest microbes after phagocytosis? |
| − | * | + | |a6= |
| − | | | + | *Glycosidases |
| − | |- | + | *Lipases |
| − | | | + | *Proteases |
| − | | | + | |l6=Innate Immune System - WikiBlood#Phagocytosis |
| − | * | + | |q7=True or False: Lysosomes do not use energy when they kill microbes |
| − | | | + | |a7= |
| − | | | + | *False |
| − | | | + | *Lysosomes fuse with phagosomes, killing microbes in an energy-dependent way |
| − | | | + | |l7=Innate Immune System - WikiBlood#Phagocytosis |
| − | * | + | |q8=Name two physical barriers of the innate immune system |
| − | | | + | |a8= |
| − | | | + | *Skin |
| − | + | *Mucous membranes | |
| − | + | |l8=Innate Immune System - WikiBlood#Pysical Barriers | |
| − | * | + | |q9=Name 3 biochemical barriers of the innate immune system |
| − | * | + | |a9= |
| − | * | + | *Lactic and fatty acids |
| − | | | + | *Enzymes |
| − | | | + | *Mucous |
| − | + | |l9=Innate Immune System - WikiBlood#Biochemical Barriers | |
| − | | | + | |q10=What is the function of commensal organisms? |
| − | + | |a10= | |
| − | * | + | *Produce natural antibiotics |
| − | | | + | *Outcompete pathogens at epithelial and mucosal surfaces |
| − | | | + | |l10=Innate Immune System - WikiBlood#Commensal Organisms |
| − | + | |q11=Complete the sentence about commensal organisms: | |
| − | || | + | <p>When commensals are disturbed, infection with ??? organisms is ???</p> |
| − | + | |a11= | |
| − | * | + | *opportunistic |
| − | | | + | *increased |
| − | | | + | |l11=Innate Immune System - WikiBlood#Commensal Organisms |
| − | + | |q12=Name the three main humoral factors and their principal action | |
| − | + | |a12= | |
| − | * | + | *Lysozyme |
| − | + | **Digests bacterial cell walls | |
| − | + | *Complement | |
| − | + | **Promotes phagocytosis or lysis of invading organisms | |
| − | | | + | *Interferons |
| − | + | **=Make uninfected cells resistant to infection | |
| − | | | + | |l12=Innate Immune System - WikiBlood#Humoral Factors |
| − | * | + | |q13=Which granulocytes are components of the innate immune response to infection? |
| − | * | + | |a13= |
| − | | | + | *Neutrophils |
| − | + | *Eosinophils | |
| − | + | *Basophils/mast cells | |
| − | | | + | |l13=Innate Immune System - WikiBlood#Cellular responses |
| − | | | + | |q14=Which other cells are components of the innate immune response to infection? |
| − | | | + | |a14=Monocytes |
| − | | | + | *Tissue mast cells |
| − | + | *Macrophages | |
| − | + | |l14=Innate Immune System - WikiBlood#Cellular responses | |
| − | + | </FlashCard> | |
| − | + | ===Innate Immunity to Viruses=== | |
| − | + | <FlashCard questions="4"> | |
| − | + | |q1=What is the main element of a viral attack which the innate immune system can recognise? | |
| − | + | |a1=Double stranded RNA (dsRNA) | |
| − | + | |l1=Innate Immune System - WikiBlood#Innate Immunity to Viruses | |
| − | + | |q2=Where are TLR3's located in the cell and what do they recognise? | |
| − | + | |a2= | |
| − | + | *Cell surface | |
| − | + | *Double stranded RNA (dsRNA) | |
| − | + | |l2=Innate Immune System - WikiBlood#Innate Immunity to Viruses | |
| − | + | |q3=What are the funtions of Type I Interferon production in response to a viral attack? | |
| − | + | |a3= | |
| − | + | *Increases mRNA degredation | |
| − | + | *Inhibits protein synthesis | |
| − | + | *Increases antigen presentation to antibody | |
| − | + | |l3=Innate Immune System - WikiBlood#Innate Immunity to Viruses | |
| − | + | |q4=Which cells are produced as the final line of response to viral attack and which cells do they target? | |
| − | + | |a4= | |
| − | + | *Natural Killer cells (NK cells) | |
| − | + | *Targets cells with decreased levels of MHC on their surface | |
| − | + | |l4=Innate Immune System - WikiBlood#Innate Immunity to Viruses | |
| − | + | </FlashCard> | |
| − | + | ===Innate Immunity to Bacteria=== | |
| − | + | <FlashCard questions="2"> | |
| − | + | |q1=What effects does the release of inflammatory cytokines have on the infected area? | |
| − | + | |a1 | |
| − | + | *=White blood cell influx | |
| − | + | *Vasodilation | |
| − | + | *Increase in vascular permeability | |
| − | + | *Sustains a rise in core temperature | |
| − | + | *Mediates the release of acute phase proteins from the liver | |
| − | + | *Mediates boone marrow mobilisation | |
| − | + | |l1=Innate Immune System - WikiBlood#Innate Immunity to Bacteria | |
| − | + | |q2=Which cell is most important in the innate response to bacterial infection? | |
| − | + | |a2=Neutrophils | |
| − | + | |l2=Innate Immune System - WikiBlood#Innate Immunity to Bacteria | |
| − | + | </FlashCard> | |
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Revision as of 11:04, 20 February 2010
|
Actions and Tools of the Innate Immune System
| Question | Answer | Article | |
| True or False: The innate immune system responds quicker to infection than the adaptive immune system | True
|
Link to Article | |
| Pathogen-associated molecular patterns (PAMPs) are expressed by which type of cells? |
|
Link to Article | |
| What recognises PAMPs? | Pattern recognition receptors (PRRs)
|
Link to Article | |
| Where in the cell are Toll-Like Receptors (TLRs) located? | Cell membrane
|
Link to Article | |
| Where in the cell are NOD2 receptors located? | Cell cytoplasm
|
Link to Article | |
| Which catabolic enzymes digest microbes after phagocytosis? |
|
Link to Article | |
| True or False: Lysosomes do not use energy when they kill microbes |
|
Link to Article | |
| Name two physical barriers of the innate immune system |
|
Link to Article | |
| Name 3 biochemical barriers of the innate immune system |
|
Link to Article | |
| What is the function of commensal organisms? |
|
Link to Article | |
| Complete the sentence about commensal organisms:
When commensals are disturbed, infection with ??? organisms is ??? |
|
Link to Article | |
| Name the three main humoral factors and their principal action |
|
Link to Article | |
| Which granulocytes are components of the innate immune response to infection? |
|
Link to Article | |
| Which other cells are components of the innate immune response to infection? | Monocytes
|
Link to Article | |
Innate Immunity to Viruses
| Question | Answer | Article | |
| What is the main element of a viral attack which the innate immune system can recognise? | Double stranded RNA (dsRNA)
|
Link to Article | |
| Where are TLR3's located in the cell and what do they recognise? |
|
Link to Article | |
| What are the funtions of Type I Interferon production in response to a viral attack? |
|
Link to Article | |
| Which cells are produced as the final line of response to viral attack and which cells do they target? |
|
Link to Article | |
Innate Immunity to Bacteria
| Question | Answer | Article | |
| What effects does the release of inflammatory cytokines have on the infected area? | Link to Article | ||
| Which cell is most important in the innate response to bacterial infection? | Neutrophils
|
Link to Article | |