Difference between revisions of "Sheep Pulmonary Adenomatosis"

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(New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Retroviridae |subtext1=RETROVIRIDAE |pagetype =Bugs }} <br> ====Antigenicity==== *The virus cannot be grown in cu...)
 
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*Nasal fluid discharges during wheelbarrow test
 
*Nasal fluid discharges during wheelbarrow test
 
*Secondary bacterial infection by ''Pasteurella hemolytica'' often precipitates death
 
*Secondary bacterial infection by ''Pasteurella hemolytica'' often precipitates death
*PM reveals fawn-gray tumor
+
*PM reveals fawn-gray tumor (for more see [[Lungs Hyperplastic and Neoplastic - Pathology#Sheep pulmonary adenomatosis (SPA/ Jaagsiekte)|here]])
  
 
====Epidemiology====
 
====Epidemiology====

Revision as of 19:25, 20 October 2008



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VIRUSES
RETROVIRIDAE



Antigenicity

  • The virus cannot be grown in culture, although it can be seen by EM on tumor cells of infected sheep

Pathogenesis

  • Causes a proliferation of alveolar lining cells, producing massive amounts of fluid
  • Proliferative foci project into alveoli and bronchi and from slow-growing tumors
  • Death occurs between 3-4 years of age

Clinical signs:

  • Low exercise tolerance
  • Gradual weight loss
  • Dyspnoea
  • Coughing
  • Nasal fluid discharges during wheelbarrow test
  • Secondary bacterial infection by Pasteurella hemolytica often precipitates death
  • PM reveals fawn-gray tumor (for more see here)

Epidemiology

  • Found in 25% of pneumonia cases in Scotland
  • Absent in USA, common in UK

Diagnosis

  • Electron microscopy on lung biopsy

Control

  • Cull clinically affected animals