3,320
edits
Changes
→Spectrum of Activity
===Spectrum of Activity===
===Spectrum of Activity===
* They are active mainly against gram-negative species, including some of the hardier species.
* They are inactive against anaerobes, this is because their action is dependent on oxygen-dependent active transport systems.
* They tend not to work well in purulent material.
===Pharmacokinetic Considerations===
===Pharmacokinetic Considerations===