Difference between revisions of "Exocrine Pancreatic Insufficiency"
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| + | <big><center>[[Pancreas Developmental - Pathology|'''BACK TO PANCREAS - DEVELOPMENTAL''']]</center></big> | ||
| + | <big><center>[[Pancreas Degenerative - Pathology|'''BACK TO PANCREAS - DEGENERATIVE''']]</center></big> | ||
| + | <big><center>[[Pancreas Inflammatory - Pathology|'''BACK TO PANCREAS - INFLAMMATORY''']]</center></big> | ||
| + | <big><center>[[Pancreas Hyperplastic and Neoplastic - Pathology|'''BACK TO PANCREAS - HYPERPLASTIC AND NEOPLASTIC''']]</center></big> | ||
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| + | *'''Exocrine pancreatic insufficiency (EPI)''' is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas | ||
| + | *Leading to insufficient activity of digestive enzymes in the lumen of the small intestine | ||
| + | *Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI | ||
| + | *Most common in dog - usually associated with [[Pancreas Degenerative - Pathology|pancreatic atrophy]] or [[Pancreas Inflammatory - Pathology#Chronic Pancreatitis|chronic pancreatitis]] | ||
| + | *Occurs occasionally in other species, esp. calves with [[Pancreas Developmental - Pathology#Pancreatic hypoplasia|pancreatic hypoplasia]] and in cats | ||
| + | *'''Clinical signs''' | ||
| + | **Steatorrhoea | ||
| + | **Diarrhoea | ||
| + | **Weight loss | ||
| + | **Increased appetite | ||
| + | |||
| + | *In contrast, '''horses''' with very little pancreatic tissue develop '''hypoinsulinism''' but rarely EPI | ||
Revision as of 11:24, 7 August 2009
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This article is still under construction. |
- Exocrine pancreatic insufficiency (EPI) is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas
- Leading to insufficient activity of digestive enzymes in the lumen of the small intestine
- Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI
- Most common in dog - usually associated with pancreatic atrophy or chronic pancreatitis
- Occurs occasionally in other species, esp. calves with pancreatic hypoplasia and in cats
- Clinical signs
- Steatorrhoea
- Diarrhoea
- Weight loss
- Increased appetite
- In contrast, horses with very little pancreatic tissue develop hypoinsulinism but rarely EPI