Difference between revisions of "Enteritis, Lymphocytic - Plasmacytic"
Line 10: | Line 10: | ||
==Description== | ==Description== | ||
− | '''Lymphocytic - plasmacytic enteritis''' (LPE) is the most common form of [[Inflammatory Bowel Disease - WikiClinical|Inflammatory Bowel Disease]]. As its name suggests, the predominant cell type in the intestinal mucosa is lymphocytes and plasma cells. Enteric parasites, bacteria in dogs and ''Toxoplasma'' in cats have been reported to associated with LPE. This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as pancreatitis, cholangitis and hepatic lipidosis. | + | '''Lymphocytic - plasmacytic enteritis''' (LPE) is the most common form of [[Inflammatory Bowel Disease - WikiClinical|Inflammatory Bowel Disease]]. As its name suggests, the predominant cell type in the intestinal mucosa is '''lymphocytes''' and '''plasma cells'''. Enteric parasites, bacteria in dogs and ''Toxoplasma'' in cats have been reported to associated with LPE. This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as pancreatitis, cholangitis and hepatic lipidosis. This disease in animal has been compared to the human dsease. LPE is believed to be caused by an abnormal MALT response to luminal bacterial, dietary or self-antigens. |
− | The small intestines is affected to a variable degree of serverity. It has also been known to affect other parts of the gastrointestinal tract such as the stomach and the colon. In severely affected animals, a protein-losing enteropathy | + | The small intestines is affected to a variable degree of serverity. It has also been known to affect other parts of the gastrointestinal tract such as the stomach and the colon. In severely affected animals, this will result in a protein-losing enteropathy (PLE). |
− | |||
− | |||
==Diagnosis== | ==Diagnosis== | ||
===Clinical Signs=== | ===Clinical Signs=== | ||
− | + | *Small intestinal diarrhoea. | |
+ | *Weight loss | ||
+ | *Protein - losing enteropathy in severe cases | ||
+ | *Chronic vomiting (common in cats, sometimes in dogs) | ||
Revision as of 08:53, 12 August 2009
This article is still under construction. |
Signalment
Basenjis have been reported to suffer from a severe form of this disease.
Description
Lymphocytic - plasmacytic enteritis (LPE) is the most common form of Inflammatory Bowel Disease. As its name suggests, the predominant cell type in the intestinal mucosa is lymphocytes and plasma cells. Enteric parasites, bacteria in dogs and Toxoplasma in cats have been reported to associated with LPE. This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as pancreatitis, cholangitis and hepatic lipidosis. This disease in animal has been compared to the human dsease. LPE is believed to be caused by an abnormal MALT response to luminal bacterial, dietary or self-antigens.
The small intestines is affected to a variable degree of serverity. It has also been known to affect other parts of the gastrointestinal tract such as the stomach and the colon. In severely affected animals, this will result in a protein-losing enteropathy (PLE).
Diagnosis
Clinical Signs
- Small intestinal diarrhoea.
- Weight loss
- Protein - losing enteropathy in severe cases
- Chronic vomiting (common in cats, sometimes in dogs)
Laboratory Tests
Haematology
Biochemistry
Other Tests
Diagnostic Imaging
Treatment
Prognosis
References
- Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition) W.B. Saunders Company.
- Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition) BSAVA
- Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.