Difference between revisions of "Leptospirosis - Cats and Dogs"
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(Created page with '**Dogs and cats ***Serovars ''canicola'' and ''icterohaemorrhagica'' cause leptospirosis in dogs, but are vaccinated against ***Serovars ''pomona'' and ''grippotyphosa'' are beco…') |
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***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host | ***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host | ||
***Infections uncommon in cats | ***Infections uncommon in cats | ||
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| + | *''Leptospirosis icterohaemorrhagica'' - a septicaemic disease which affects the [[Liver - Anatomy & Physiology|liver]] | ||
| + | *puppies | ||
| + | *Leptospirosis is an important spirochaetal group of diseases causing disease in animals and humans (zoonotic) | ||
| + | *Transmission | ||
| + | **via urine of affected animals | ||
| + | **organisms can remain viable for weeks in damp conditions | ||
| + | *method of action | ||
| + | **cause anaemia via intravascular haemolysis | ||
| + | =====Clinical===== | ||
| + | *fever | ||
| + | *dehydration | ||
| + | *haemorrhaging from the mucous membranes of the body | ||
| + | =====Diagnosis===== | ||
| + | *dark field microscopy on fresh urine is best | ||
| + | =====Gross===== | ||
| + | *widespread hameorrhages | ||
| + | *icterus | ||
| + | *pale foci in the [[Liver - Anatomy & Physiology|liver]] (not always a constant finding) | ||
| + | *subcapsular and cortical renal haemorrhages | ||
| + | =====Microscopically===== | ||
| + | *foci of necrosis | ||
| + | *dissociation of hepatocytes form each other (similar to post mortem change) | ||
| + | *substantial haemosiderin in the Kuppfer cells (from the haemolysis) | ||
| + | *need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues | ||
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[[Category:Leptospiraceae]][[Category:Cat]][[Category:Dog]] | [[Category:Leptospiraceae]][[Category:Cat]][[Category:Dog]] | ||
| + | [[Category:Hepatitis,_Bacterial]] | ||
Revision as of 14:16, 7 June 2010
- Dogs and cats
- Serovars canicola and icterohaemorrhagica cause leptospirosis in dogs, but are vaccinated against
- Serovars pomona and grippotyphosa are becoming important
- The host-adapted serovar canicolar causes acute renal failure in puppies; a chronic uraemic syndrome may follow
- Incidental infections with serovar icterohaemorrhagica or copenhagenii cause renal failure
- L. icterohaemorrhagiae may cause hepatic jaundice
- Serovar bratislava causes abortion and infertility in dogs, which may be the maintenance host
- Infections uncommon in cats
- Dogs and cats
- Leptospirosis icterohaemorrhagica - a septicaemic disease which affects the liver
- puppies
- Leptospirosis is an important spirochaetal group of diseases causing disease in animals and humans (zoonotic)
- Transmission
- via urine of affected animals
- organisms can remain viable for weeks in damp conditions
- method of action
- cause anaemia via intravascular haemolysis
Clinical
- fever
- dehydration
- haemorrhaging from the mucous membranes of the body
Diagnosis
- dark field microscopy on fresh urine is best
Gross
- widespread hameorrhages
- icterus
- pale foci in the liver (not always a constant finding)
- subcapsular and cortical renal haemorrhages
Microscopically
- foci of necrosis
- dissociation of hepatocytes form each other (similar to post mortem change)
- substantial haemosiderin in the Kuppfer cells (from the haemolysis)
- need to use a silver stain or immunofluorescence to demonstrate the organisms in tissues