Difference between revisions of "Sheep Pulmonary Adenomatosis"
Jump to navigation
Jump to search
| Line 28: | Line 28: | ||
*Cull clinically affected animals | *Cull clinically affected animals | ||
[[Category:Mammalian Type D retrovirus ]][[Category:Sheep]] | [[Category:Mammalian Type D retrovirus ]][[Category:Sheep]] | ||
| + | [[Category:To_Do_-_Viruses]] | ||
Revision as of 22:57, 26 June 2010
 |
This article is still under construction. |
Antigenicity
- The virus cannot be grown in culture, although it can be seen by EM on tumor cells of infected sheep
Pathogenesis
- Causes a proliferation of alveolar lining cells, producing massive amounts of fluid
- Proliferative foci project into alveoli and bronchi and from slow-growing tumors
- Death occurs between 3-4 years of age
Clinical signs:
- Low exercise tolerance
- Gradual weight loss
- Dyspnoea
- Coughing
- Nasal fluid discharges during wheelbarrow test
- Secondary bacterial infection by Pasteurella hemolytica often precipitates death
- PM reveals fawn-gray tumor (for more see here)
Epidemiology
- Found in 25% of pneumonia cases in Scotland
- Absent in USA, common in UK
Diagnosis
- Electron microscopy on lung biopsy
Control
- Cull clinically affected animals