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| − | ===Oedema Disease In The Pig=== | + | ===[[Oedema Disease]] In The Pig=== |
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| − | * '''Catarrhal gastritis is an important characterisitic of this condition'''
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| − | * Oedema disease is a sporadic condition that can become important on some farms.
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| − | ====Clinical====
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| − | * Generally occurs in young pigs, though sometimes in older pigs
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| − | ** 7-10 days after major change in diet e.g. weaning.
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| − | * Signs include
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| − | ** '''No''' [[Intestine Diarrhoea - Pathology|diarrhoea]]
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| − | ** Puffy eyelids
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| − | ** High-pitched voice (oedema of larynx)
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| − | ** Sitting on haunched
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| − | ** "Star-gazing" due to cerebral oedema (hallucinations?).
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| − | * Animals usually die.
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| − | * Disease develops very quickly so pigs do not have time to go off food.
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| − | ====Pathogenesis====
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| − | * Oedema disease is an enterotoxaemia associated with infection by enterotoxigenic [[Escherichia coli|''E.coli'']].
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| − | * Verotoxin/ shiga toxin- producing ''E. coli'' proliferate in the [[Small Intestine - Anatomy & Physiology|small intestine]]
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| − | ** Especially O138, O139, and O141.
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| − | ** Organisms remain in the gut (are not invasive).
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| − | * Labile shiga-like toxin II is absorbed into body, producing effects everywhere.
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| − | * Blood vessel walls are damaged and become very leaky, producing oedema everywhere.
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| − | ** Histological blood vessel changes are subtle.
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| − | ** Fibrinoid degeneration of media in small arteries.
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| − | ====Pathology====
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| − | * An important characteristic of oedema disease is the occurrence of catarrhal gastritis and marked oedema in the [[Forestomach - Anatomy & Physiology|stomach]] mucosa and wall.
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| − | * Also oedema of various organs, particularly between coils of spiral [[Colon - Anatomy & Physiology|colon]].
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| − | ====Diagnosis====
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| − | * Clinical signs are characteristic.
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| − | * Also by culture and typing of ''E. coli'' from gut
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| | ==Erosive and Ulcerative Gastritis == | | ==Erosive and Ulcerative Gastritis == |