Difference between revisions of "Haemangiosarcoma"
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*Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) '''BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition)''' ''BSAVA'' | *Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) '''BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition)''' ''BSAVA'' | ||
*Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine (Fourth Edition)''' ''Mosby Elsevier''. | *Nelson, R.W. and Couto, C.G. (2009) '''Small Animal Internal Medicine (Fourth Edition)''' ''Mosby Elsevier''. | ||
| + | |||
| + | ==From Pathology== | ||
| + | |||
| + | ===Cholangiocellular - bile duct=== | ||
| + | *can be primary in the [[Liver - Anatomy & Physiology|liver]] | ||
| + | *other predilection sites | ||
| + | **[[Spleen - Anatomy & Physiology|spleen]] | ||
| + | **right auricle of the heart | ||
| + | *prevalent in large breeds | ||
| + | |||
| + | [[Category:Liver,_Primary_Tumours]] | ||
| + | |||
[[Category:Peritoneal_Cavity_-_Neoplastic_Pathology]][[Category:To_Do_-_Clinical]] | [[Category:Peritoneal_Cavity_-_Neoplastic_Pathology]][[Category:To_Do_-_Clinical]] | ||
Revision as of 13:07, 28 June 2010
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This article is still under construction. |
Signalment
- Often found in older German Shepherd Dogs and Golden Retrievers
Golden RetrieverWikiCommons
German Shepherd (Alsatian)WikiCommons
Description
The origin of abdominal haemangiosarcoma is often from the spleen. Neoplastic cells are implanted into the abdomen, causing widespread peritoneal seepage of blood or metastasise to the liver and lungs. This is a highly malignant disease.
Diagnosis
Clinical Signs
- Collapse; due to rupture of the mass, leading to a haemoabdomen
- Abdominal effusion
- Lethargy, weakness, pallor and anorexia may preceed a major bleed
Laboratory Tests
Haematology
- Anaemia; may be regenerative if due to blood loss, or microangiopathic due to the passage of red blood cells through the microvascular network of the tumour
Biochemistry
Other Tests
Diagnostic Imaging
Radiography
This may be able to reveal any masses, provided there is minimal peritoneal fluid.
Ultrasonography
This is sensitive in indentifying liver and splenic masses.
Histopathology
Biopsy of any masses will provide a definitive diagnosis. This is needed to differentiate haemangiosarcoma from splenic haematoma, haemangioma and accessory splenic tissue.
Treatment
Surgery
This is useful if there are any solitary masses that can be excised.
Chemotherapy
This will provide a palliative treatment for animals with multiple masses or as an adjuvant therapy post-operatively.
Prognosis
Poor due to high risk of metastasis in the early course of the disease.
References
- Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition) W.B. Saunders Company.
- Hall, E.J, Simpson, J.W. and Williams, D.A. (2005) BSAVA Manual of Canine and Feline Gastroenterology (2nd Edition) BSAVA
- Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.