Difference between revisions of "Sporothrix schenckii"

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*Caused by [[Sporothrix schenckii|''Sporothrix schenckii'']]
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*Cutaneous, may involve lymhatic vessels or disseminate
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*Occurs in horses, cattle, cats and dogs
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*Grossly:
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[[Image:Sporotrichosis horse.jpg|thumb|right|150px|Sporotrichosis in a horse -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]]
**Ulcerated cutaneous nodules
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[[Image:Sporotrichosis cigar cells.jpg|thumb|right|150px|Sporotrichosis cigar shaped cells -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath]]
**Fistulas may form
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*''Sporothrix schenckii''
*Microscopically:
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**Hard to find ovoid to elongated organisms
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*Occurs in soil, wood and vegetation
**More numerous in cats
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**Saprophyte of both decaying and healthy vegetation
*Exudate may be infectious to humans if comes into contact with wounds
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*Worldwide
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*Exogenous infections through wounds
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*Sporadic infections
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*Non-contageous
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*Causes subcutaneous nodules or granulomas
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**Nodules ulcerate discharging pus
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*Spread via the [[Lymphatic System - Anatomy & Physiology|lymphatics]]
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*The [[Bones and Cartilage - Anatomy & Physiology|bones]] and viscera can be involved which terminates in mortality
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**This is rare
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**Reported in dogs and horses
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*Affects dogs, horses, cats, monkeys, mules, camels, donkeys, cattle, fowl and rodents
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**Most commonly seen in horses as an ascending lymphocutaneous infection of the legs
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**Can be confused with [[Subcutaneous Mycoses#Epizootic Lymphangitis|epizootic lymphangitis]] in horses
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*Single cell, cigar shaped
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**Usually found within [[Neutrophils|neutrophils]]
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**Yeast cell clusters with peripheral eosinophilic rays can be seen in tissue sections
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*Stained using PAS, Gram stain (positive), fluorescent antibody and Calcofluor White
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*Latex agglutination and immunodiffusion serology can be performed
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*Grows on Blood agar and Sabouraud's Dextrose agar in one to three weeks
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**At 37°C:
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***Colonies are smooth, cream to tan coloured and soft
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***No mycelium can be seen
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**At 25°C to 27°C:
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***Colonies turn from white and soft to tan to brown to black
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***Leathery, wrinkled and coarse
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***Mycelium can be seen as branching septate hyphae
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***Conidiospores can also be seen
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*Potassium iodide treatment orally
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**[[Antifungal Drugs#Flucytosine|5-fluorocytosine]] and [[Antifungal Drugs#Polyene Antifungals|amphotericin B]] can also be used[[Category:Subcutaneous_Mycoses]]
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[[Category:To_Do_-_Fungi]]

Revision as of 11:33, 30 June 2010


Sporotrichosis in a horse -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath
Sporotrichosis cigar shaped cells -Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath
  • Sporothrix schenckii
  • Occurs in soil, wood and vegetation
    • Saprophyte of both decaying and healthy vegetation
  • Worldwide
  • Exogenous infections through wounds
  • Sporadic infections
  • Non-contageous
  • Causes subcutaneous nodules or granulomas
    • Nodules ulcerate discharging pus
  • The bones and viscera can be involved which terminates in mortality
    • This is rare
    • Reported in dogs and horses
  • Affects dogs, horses, cats, monkeys, mules, camels, donkeys, cattle, fowl and rodents
    • Most commonly seen in horses as an ascending lymphocutaneous infection of the legs
    • Can be confused with epizootic lymphangitis in horses
  • Single cell, cigar shaped
    • Usually found within neutrophils
    • Yeast cell clusters with peripheral eosinophilic rays can be seen in tissue sections
  • Stained using PAS, Gram stain (positive), fluorescent antibody and Calcofluor White
  • Latex agglutination and immunodiffusion serology can be performed
  • Grows on Blood agar and Sabouraud's Dextrose agar in one to three weeks
    • At 37°C:
      • Colonies are smooth, cream to tan coloured and soft
      • No mycelium can be seen
    • At 25°C to 27°C:
      • Colonies turn from white and soft to tan to brown to black
      • Leathery, wrinkled and coarse
      • Mycelium can be seen as branching septate hyphae
      • Conidiospores can also be seen