Difference between revisions of "Newcastle Disease Virus"
| Line 4: | Line 4: | ||
====Hosts==== | ====Hosts==== | ||
| − | + | Gallinaceous birds, pigeons, parrots, finches | |
| − | + | ||
| − | + | Subclinical carriers: ducks, ostriches | |
| + | |||
====Pathogenesis==== | ====Pathogenesis==== | ||
| − | + | Transmission via aerosol and direct contact | |
| − | + | Disease ranges from subclinical respiratory tract infections -> torticollis -> haemorrhages and death | |
====Diagnosis==== | ====Diagnosis==== | ||
Two diagnostic tests currently exist: | Two diagnostic tests currently exist: | ||
| − | + | Animal test: | |
| − | + | 1. Samples of trachea and gut of 20 birds are tested in eggs | |
| − | + | '''HI''' using anti-NDV serum (to differentiate '''HA''' caused by [[Avian Influenza]] | |
| − | + | Virulence of isolate tested by the speed it kills chicks | |
| − | + | ||
| − | + | 2. DNA test (which will soon replace the animal test): | |
| − | + | Sequencing the cleavage site of H gene | |
| + | The more basic amino acids the more virulent the virus | ||
====Control==== | ====Control==== | ||
Revision as of 18:26, 27 July 2010
Newcastle disease is a virus from the family Paramyxoviridae. Avian paramyxovirus 1 affects chickens, ducks, pheasants, geese and turkeys. The virus is stable in carcasses for weeks, so has the potential to affect a large amount of
Hosts
Gallinaceous birds, pigeons, parrots, finches
Subclinical carriers: ducks, ostriches
Pathogenesis
Transmission via aerosol and direct contact Disease ranges from subclinical respiratory tract infections -> torticollis -> haemorrhages and death
Diagnosis
Two diagnostic tests currently exist: Animal test: 1. Samples of trachea and gut of 20 birds are tested in eggs HI using anti-NDV serum (to differentiate HA caused by Avian Influenza Virulence of isolate tested by the speed it kills chicks
2. DNA test (which will soon replace the animal test): Sequencing the cleavage site of H gene The more basic amino acids the more virulent the virus
Control
- Newcastle Disease is NOTIFIABLE
- Vaccination of chickens and racing pigeons
- Surveillance of imported exotic birds
- Isolation of infected stock
- Infected premises to be culled and firebreak cull if spread