Difference between revisions of "Avian Influenza"
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m (Text replace - "Category:To_Do_-_Viruses" to "Category:To_Do_-_Clinical/Viruses") |
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− | {{unfinished}} | + | {{unfinished}} |
− | ===Subtypes=== | + | === Subtypes === |
− | *H1-15 and N1-9 have all been isolated | + | |
+ | *H1-15 and N1-9 have all been isolated | ||
*Highly Pathogenic Avian Influenza (HPAI), caused by H5 and H7 isolates, is also known as Fowl Plague (FP) and is notifiable | *Highly Pathogenic Avian Influenza (HPAI), caused by H5 and H7 isolates, is also known as Fowl Plague (FP) and is notifiable | ||
**Chinese poultry are currently the main reservoir for H5N1, not wild birds | **Chinese poultry are currently the main reservoir for H5N1, not wild birds | ||
− | ===Pathogenesis=== | + | |
− | *HPAI is defined by: | + | === Pathogenesis === |
− | **Heamorrhages | + | |
− | **Diarrhoea | + | *HPAI is defined by: |
− | **Sometimes nervous symptoms | + | **Heamorrhages |
− | **Sudden death | + | **Diarrhoea |
− | *H5 spread by feces and infected viscera (kidney/spleen are 100X more infectious than feces) | + | **Sometimes nervous symptoms |
− | *H7 and other viruses are carried by 6% of the wild bird population and outbreaks mirror migrating patterns | + | **Sudden death |
+ | *H5 spread by feces and infected viscera (kidney/spleen are 100X more infectious than feces) | ||
+ | *H7 and other viruses are carried by 6% of the wild bird population and outbreaks mirror migrating patterns | ||
**This poses significant risk to free-range flocks | **This poses significant risk to free-range flocks | ||
− | ===Zoonotic potential=== | + | |
− | *A 2003 Dutch outbreak of a pathogenic H7 virus caused widespread conjunctivitis and flu-like symptoms with recovery among poultry workers | + | === Zoonotic potential === |
+ | |||
+ | *A 2003 Dutch outbreak of a pathogenic H7 virus caused widespread conjunctivitis and flu-like symptoms with recovery among poultry workers | ||
*Rural chinese children became infected with H5N1 via aerosol transmission, which was limited to upper respiratory symptoms and did not show horizontal spread | *Rural chinese children became infected with H5N1 via aerosol transmission, which was limited to upper respiratory symptoms and did not show horizontal spread | ||
− | ===Control=== | + | |
− | *Prevention by proper hygiene and preventing contact with the wild bird population | + | === Control === |
− | *Isolation and cull of infected premises | + | |
− | *Firebreak cull in the case of uncontrolled spread | + | *Prevention by proper hygiene and preventing contact with the wild bird population |
− | *Vaccination is not currently practiced for the following reasons: | + | *Isolation and cull of infected premises |
− | **An eradication policy prevents it | + | *Firebreak cull in the case of uncontrolled spread |
+ | *Vaccination is not currently practiced for the following reasons: | ||
+ | **An eradication policy prevents it | ||
**Vaccination favors the evolution of the virus, which might increase its virulence and drift | **Vaccination favors the evolution of the virus, which might increase its virulence and drift | ||
− | [[Category:Orthomyxoviridae]][[Category: | + | |
− | [[Category:To_Do_-_Clinical/Viruses]] | + | [[Category:Orthomyxoviridae]] [[Category:Avian Viruses]] [[Category:To_Do_-_Clinical/Viruses]] |
Revision as of 16:49, 24 January 2011
This article is still under construction. |
Subtypes
- H1-15 and N1-9 have all been isolated
- Highly Pathogenic Avian Influenza (HPAI), caused by H5 and H7 isolates, is also known as Fowl Plague (FP) and is notifiable
- Chinese poultry are currently the main reservoir for H5N1, not wild birds
Pathogenesis
- HPAI is defined by:
- Heamorrhages
- Diarrhoea
- Sometimes nervous symptoms
- Sudden death
- H5 spread by feces and infected viscera (kidney/spleen are 100X more infectious than feces)
- H7 and other viruses are carried by 6% of the wild bird population and outbreaks mirror migrating patterns
- This poses significant risk to free-range flocks
Zoonotic potential
- A 2003 Dutch outbreak of a pathogenic H7 virus caused widespread conjunctivitis and flu-like symptoms with recovery among poultry workers
- Rural chinese children became infected with H5N1 via aerosol transmission, which was limited to upper respiratory symptoms and did not show horizontal spread
Control
- Prevention by proper hygiene and preventing contact with the wild bird population
- Isolation and cull of infected premises
- Firebreak cull in the case of uncontrolled spread
- Vaccination is not currently practiced for the following reasons:
- An eradication policy prevents it
- Vaccination favors the evolution of the virus, which might increase its virulence and drift