Difference between revisions of "Porcine Parvovirus"

From WikiVet English
Jump to navigation Jump to search
Line 33: Line 33:
 
SMEDI syndrome leading to stillbirth, mummification, embryonic death or infertility.  
 
SMEDI syndrome leading to stillbirth, mummification, embryonic death or infertility.  
  
[[Category:Parvoviridae]][[Category:Pig]]
+
[[Category:Parvoviridae]][[Category:Pig Viruses]]
 +
[[Category:Reproductive Diseases - Pig]]
 
[[Category:To_Do_-_Clinical/Viruses]]
 
[[Category:To_Do_-_Clinical/Viruses]]

Revision as of 18:40, 17 January 2011



Antigenicity

  • Single serotype

Hosts

  • Pigs

Pathogenesis

  • Principal viral cause of SMEDI syndrome: Stillbirths, Mummification, Embryonic Deaths, and Infertility
  • Replicates in gastrointestinal epithelium followed by viremia
  • Often no clinical signs in breeding and growing stock
  • Transplacental infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers

Epidemiology

  • About 50% of UK pigs are antibody-positive
  • Transfer is orofecal or via fomites
  • Outbreaks occur as herd is developing immunity
  • Congenitally infected piglets act as herd reservoir

Diagnosis

  • Immunostaining of fetal tissues
  • Virus isolation in cell culture
  • HA on feces
  • Rising antibody titres in paired serum sample by HAI

Control

  • Inactivated vaccine (UK) or live attenuated (USA)
  • Infected piglets should be culled


SMEDI syndrome leading to stillbirth, mummification, embryonic death or infertility.