Difference between revisions of "Bacillary Haemoglobinuria"
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Revision as of 09:45, 4 August 2010
Italic text
This article is still under construction. |
Also known as: | Red Water Clostridium novyi Type D |
Description
Adisease of cattle and sheep caused by Clostridium haemolyticum.which is a bacteria from the class clostridia. C. haemolyticum is found in soil, poorly drained/wet pastures and is highly fatal to livestock. The bacteria produces a beta toxin and causes hepatic necrosis and intravascular haemolysis. The disease is often associated with a disease in the liver causing anaerobic conditions allowing the groeth of bacteria and hence toxin production.
- spores found routinely in liver and GIT and faeces of grazing animals in affected pastures
- need disease in liver casing anaerobic conditions to allow bacterial growth and toxin production
- normally associated with Liver Fluke damage
- disease occurs in some areas and some farms - distribution is poorly understood
Clinical Signs
- found dead/sudden death
- IF seen alive
- depressed, reluctant to move, pyrexia, respiratory distress
- red urine (haemoglobinuria) but not consistent
- pale mucous membranes/jaundice
- bloody froth in nostrils
Gross
- post mortem is confirmatory finding
- rapid decomposition of carcass
- organs decomposed
- subcutaneous hameorrhages, odema, emphysema
- blood stained abdominal and thoracic fluid, large quantity and pericardium
- animal is severely anaemic
- may be jaundiced
- red urine in bladder, therefore haemoglobin in urine
- kidneys speckled with haemoglobin
- blood in lungs/trachea
- ischaemic hepatic infarct
- usually a single large necrotic focus in the liver
- area of necrosis, sometimes partially liquefied centre, irregular outline with a hyperaemic edge
Microscopically
- presence of Clostridia post mortem must be interpreted with great caution as they are common post mortem invaders
- FAT for organism
- identification of toxins
- need this for diagnosis
Treatment
- unlikely
- very high doses of penicillin or oxytetracycline
- blood transfusion
Prevention
- vaccination lasts up to 6 months
- liver fluke control
- remove infected carcasses from pasture
NB: Distinguish Red Water from Black Disease! The former will have bleeding out of any orifice while the latter does not