Difference between revisions of "Ethylene Glycol Toxicity"
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==Introduction== | ==Introduction== | ||
| − | Ethylene Glycol is a sweet tasting fluid that is the main constituent of anti-freeze products.<ref name="multiple">'''The 5-Minute Veterinary Consult, Canine and Feline''', ''Lippencott, Williams and Wilkins''</ref>. Consequently in colder climates ethylene glycol toxicity is frequently encountered in practice. It has a relatively low minimum lethal dose, and its sweet, palatable taste makes it attractive to dogs, cats and other small animals. <ref | + | Ethylene Glycol is a sweet tasting fluid that is the main constituent of anti-freeze products.<ref name="multiple">'''The 5-Minute Veterinary Consult, Canine and Feline''', ''Lippencott, Williams and Wilkins''</ref>. Consequently in colder climates ethylene glycol toxicity is frequently encountered in practice. It has a relatively low minimum lethal dose, and its sweet, palatable taste makes it attractive to dogs, cats and other small animals. <ref>'''The 5-Minute Veterinary Consult, Canine and Feline''' (Second Edition),''lippencott, Williams and Wilkins </ref>, |
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===Pathology=== | ===Pathology=== | ||
==Treatment== | ==Treatment== | ||
| − | Ethylene Glycol is a weak acid. Therefore in order to increase the rate of renal clearance sodium bicarbonate can be administered to dogs. Intravenous administration of sodium bicarbonate at a concentration of 1-2 mmol/kg every 3 to 6 hours achieves sufficient alkalinisation of the urine.<ref | + | Ethylene Glycol is a weak acid. Therefore in order to increase the rate of renal clearance sodium bicarbonate can be administered to dogs. Intravenous administration of sodium bicarbonate at a concentration of 1-2 mmol/kg every 3 to 6 hours achieves sufficient alkalinisation of the urine.<ref>'''Canine Medicine and Therapeutics''' (Fourth Edition, 1998),''Blackwell Science'', p1049 </ref> |
==Prognosis== | ==Prognosis== | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 14:00, 30 October 2010
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This article is still under construction. |
Introduction
Ethylene Glycol is a sweet tasting fluid that is the main constituent of anti-freeze products.[1]. Consequently in colder climates ethylene glycol toxicity is frequently encountered in practice. It has a relatively low minimum lethal dose, and its sweet, palatable taste makes it attractive to dogs, cats and other small animals. [2],
Signalment
Diagnosis
Clinical Signs
Laboratory Tests
Pathology
Treatment
Ethylene Glycol is a weak acid. Therefore in order to increase the rate of renal clearance sodium bicarbonate can be administered to dogs. Intravenous administration of sodium bicarbonate at a concentration of 1-2 mmol/kg every 3 to 6 hours achieves sufficient alkalinisation of the urine.[3]