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Labrador cross with mass on antebrachium (view source)
Revision as of 18:00, 28 September 2012
, 18:00, 28 September 2012no edit summary
feedback3="'''Incorrect'''. Correct technique for a histopathological diagnosis, including an idea of behaviour. However, it would be best to perform FNA before histopathology, in case a diagnosis can be reached using cytology only (e.g. lipoma, mast cell tumour, abscess)."
feedback3="'''Incorrect'''. Correct technique for a histopathological diagnosis, including an idea of behaviour. However, it would be best to perform FNA before histopathology, in case a diagnosis can be reached using cytology only (e.g. lipoma, mast cell tumour, abscess)."
feedback4="'''Correct'''. It is best to perform FNA before histopathology, in case a diagnosis can be reached using cytology only (e.g. lipoma, mast cell tumour, abscess.) The FNA reveals blood only, but suspicion of sarcoma is increased, as sarcomas do not exfoliate cells readily and it is common to aspirate blood with soft-tissue sarcomas. Abscess and lipoma are ruled out, and a mast cell tumour is unlikely. You proceed to incisional biopsy (technique as described in option 3)."
feedback4="'''Correct'''. It is best to perform FNA before histopathology, in case a diagnosis can be reached using cytology only (e.g. lipoma, mast cell tumour, abscess.) The FNA reveals blood only, but suspicion of sarcoma is increased, as sarcomas do not exfoliate cells readily and it is common to aspirate blood with soft-tissue sarcomas. Abscess and lipoma are ruled out, and a mast cell tumour is unlikely. You proceed to incisional biopsy (technique as described in option 3)."
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{| class="mw-collapsible mw-collapsed wikitable"
! Histopathology report
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| '''Gross pathology'''<br>One pot is submitted:biopsy of the leg.<br>A pece of pale tan resilient tissue measuring 7 x 5 x 5 mm. A representative section is placed in Cassette A.<br><br>'''Histopathology'''<br>This is a section of a tumour composed of sheets of neoplastic pleomorphic polyhedral to spindle cells with a mitotic index approximating 1-2 mitoses per high power field. They are accompanied by minimal collagen. The neoplastic cells have mild karyomegaly and nucleolar prominence together with abundant eosinophilic, vacuolated cytoplasm.<br><br>'''Diagnosis'''<br>Cutaneous soft-tissue sarcoma, grade 2.<br><br>'''Comments'''<br>This diagnosis is in keeping with the previous cytological findings. The minimal collagen and cytoplasmic vacuolation evident in this case raises the possibility of liposarcoma as a more specific diagnosis.<br>In any case, this tumour is likely to be characterized by infiltrative local growth but negligible tendency for metastatic spread.
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