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==Introduction==
 
==Introduction==
Given the low compliance rate with brushing, other measures are often sought. The [[Antiseptics for Oral Disease#Antiplaque Agents|chlorhexidine mouth washes]] and gels are an excellent second best.  '''Chlorhexidine''' is a synthetic cationic bisbiguanide antimicrobial agent which is the '''most effective chemical agent''' available for the '''prevention and reduction of plaque accumulation and [[gingivitis]]'''. It has a broad spectrum of activity meaning that it has a good killing effect on many of the bacteria present in the mouth. The main advantage of chlorhexidine is that it not only '''binds to the pellicle reducing further accumulation of plaque''' on the tooth surface, but also '''eliminates existing plaque'''. It has an ability to bind to the oral tissues as well as the teeth and some studies have shown that it remains active for up to 12 hours following application. Most other oral antiseptics are washed away by saliva. The concentration that should be used is 0.12% to achieve these best results.  
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Given the low compliance rate with brushing, other measures to maintain oral hygiene are often sought. [[Antiseptics for Oral Disease#Antiplaque Agents|Chlorhexidine mouth washes]] and gels are an excellent second best.  '''Chlorhexidine''' is a synthetic cationic bisbiguanide antimicrobial agent which is the '''most effective chemical agent''' available for the '''prevention and reduction of plaque accumulation and [[gingivitis]]'''. It has a broad spectrum of activity which means it has a good killing effect on many of the bacteria present in the mouth. The main advantage of chlorhexidine is that it not only '''binds to the pellicle reducing further accumulation of plaque''' on the tooth surface, but also '''eliminates existing plaque'''. It has an ability to bind to the oral tissues as well as the teeth and some studies have shown that it remains active for up to 12 hours following application. Most other oral antiseptics are washed away by saliva. The concentration that should be used to achieve best results is 0.12% .  
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Chlorhexidine is a very unstable molecule though and if swallowed becomes inactivated. This means it is well tolerated by most pets and would not have any side effects if swallowed. In some animals chlorhexidine can cause a slight staining of the teeth. This is purely a cosmetic issue and the advantages of using chlorhexidine to reduce the inflammation in the mouth should outweigh the negative effects.  
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Chlorhexidine is a very unstable molecule and if swallowed becomes inactivated. It is therefore well tolerated by most pets and does not have any side effects if swallowed. In some animals chlorhexidine can cause slight staining of the teeth. This is a purely cosmetic issue and the advantages of using chlorhexidine to reduce the inflammation in the mouth should outweigh the negative effects.  
    
==Application==
 
==Application==
The mouthwashes can be used by applying them to the toothbrush instead of a toothpaste or on cotton buds to rub along the gum margin. They can also be used by syringing into the mouth although this is not as effective as application directly on to the tooth surface. A chlorhexidine gel can be applied directly on to the tooth surface with a finger if the pet allows.  
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Mouthwashes can be used by applying them to a toothbrush instead of a toothpaste or on cotton buds to rub along the gum margin. They can also be used by syringing into the mouth, although this is not as effective as application directly onto the tooth surface. Chlorhexidine gel can be applied directly on to the tooth surface with a finger if the pet allows.  
    
==Formulations==
 
==Formulations==
Some products are available on the market that do contain chlorhexidine but they are either at too low a concentration for the chlorhexidine to be effective or are in a formulation where the chlorhexidine may not be released or may be inactivated.  
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Some products are available on the market that do contain chlorhexidine but they are either at too low a concentration for the chlorhexidine to be effective, or are in a formulation where the chlorhexidine is not released or is inactivated.  
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Another mouth wash or gel available containing zinc, ascorbic acid (vitamin C) and taurine may also be of benefit. Zinc is antibacterial and important for healthy epithelium. Vitamin C is important in the production of collagen, which is the main structural protein in gingival tissue. The taurine chelates volatile sulphur compounds produced by oral pathogens, which has an obvious effect of reducing halitosis and may reduce the damage to oral tissues that may be caused by these volatile sulphur compounds. The gel is tasteless and alcohol-free. It has also found a use as a plaque retardant in cats that will tolerate no other forms of home-care.  
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Another mouth wash or gel available containing zinc, ascorbic acid (vitamin C) and taurine may also be of benefit. Zinc is antibacterial and important for a healthy epithelium. Vitamin C is important for the production of collagen, which is the main structural protein in gingival tissue. The taurine chelates volatile sulphur compounds produced by oral pathogens, which has an obvious effect of reducing halitosis and may reduce the damage to oral tissues that can be caused by these volatile sulphur compounds. The gel is tasteless and alcohol-free. It has also found a use as a plaque retardant in cats that will tolerate no other forms of home-care.  
    
A range of other chemical products are available that are recommended either as a food additive, water additive, or to apply directly to the pets mouth. Unfortunately there are few, if any, scientific studies to show that these products are effective in reducing [[gingivitis]] and the onset of [[periodontitis]]. Many of these products can be expensive with little or no benefit. Always ask about what clinical data is available to show that the product works before using it.  
 
A range of other chemical products are available that are recommended either as a food additive, water additive, or to apply directly to the pets mouth. Unfortunately there are few, if any, scientific studies to show that these products are effective in reducing [[gingivitis]] and the onset of [[periodontitis]]. Many of these products can be expensive with little or no benefit. Always ask about what clinical data is available to show that the product works before using it.  

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