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<p>In the paracortex region of [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] binding to MHC II and the presence of Il-4 produced by [[Lymphocytes - WikiBlood#Helper CD4+|CD4<sup>+</sup> T cells]] (Th2 type) causes [[Lymphocytes - WikiBlood#B cells|B cells]] to differentiate. Most [[Lymphocytes - WikiBlood#B cells|B cells]] become [[#Plasma cells|plasma cells]], however small number become [[#Memory cells|memory cells]] .</p>
<p>In the paracortex region of [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] binding to MHC II and the presence of Il-4 produced by [[Lymphocytes - WikiBlood#Helper CD4+|CD4<sup>+</sup> T cells]] (Th2 type) causes [[Lymphocytes - WikiBlood#B cells|B cells]] to differentiate. Most [[Lymphocytes - WikiBlood#B cells|B cells]] become [[#Plasma cells|plasma cells]], however small number become [[#Memory cells|memory cells]] .</p>
==Follicular Dendritic Cells==
==Follicular Dendritic Cells==
Follicular dendritic cell are present in the follicles. They absorb the whole of the antigen onto their surface to present to B cells to stimulate an immune response.
Follicular dendritic cell are present in the follicles. They absorb the whole of the antigen onto their surface to present to [[Lymphocytes - WikiBlood#B cells|B cells]] to stimulate an immune response.
==Plasma cells==
==Plasma cells==
===Appearance===
===Appearance===