469
edits
Changes
Jump to navigation
Jump to search
→2. Granulomatous
* Intense activation of T cells, [[Cytokines - WikiBlood|cytokine]] release and [[Macrophages - WikiBlood|macrophage]] activation cause necrosis of surrounding tissue, granuloma formation leading to destruction of host tissue.
* Intense activation of T cells, [[Cytokines - WikiBlood|cytokine]] release and [[Macrophages - WikiBlood|macrophage]] activation cause necrosis of surrounding tissue, granuloma formation leading to destruction of host tissue.
* Composed of epithelial cell, [[Macrophages - WikiBlood#Giant cells|giant cells]] and [[Macrophages - WikiBlood|macrophage]] in response to infection, for example:
* Composed of epithelial cell, [[Macrophages - WikiBlood#Giant cells|giant cells]] and [[Macrophages - WikiBlood|macrophage]] in response to infection, for example:
** ''Mycobacterium tubercle''
** [[Mycobacteria spp.|''Mycobacterium tubercle'']]
** Schistosome eggs
** Schistosome eggs
* Granulomas can obstruct normal organ function:
* Granulomas can obstruct normal organ function: