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Puberty is the process of aquiring reproductive capability. The onset depends on the ability of specific hypothalamic neurons to produce GnRH in sufficient quantities to both promote and support gametogenesis.
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* In the female, hypothalamic GnRH neurons must develop the ability to respond to positive oestradiol feedback in order to produce sufficient GnRH to cause ovulation.
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* Develepment of hypothalamic neurons is influenced by:
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** Development of a threshold body size.
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** Exposure to environmental and social cues.
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** Genetics
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