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28 bytes removed ,  17:07, 4 September 2010
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Text replace - "Oral Cavity - Tongue - Anatomy & Physiology" to "Tongue - Anatomy & Physiology"
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**RNA must be purified before converting to DNA for PCR
 
**RNA must be purified before converting to DNA for PCR
 
**False positives can occur easily by contamination with previously amplified DNA
 
**False positives can occur easily by contamination with previously amplified DNA
*May see animals that have discoloration of [[Oral Cavity - Tongue - Anatomy & Physiology|tongue]] due to having had FMD
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*May see animals that have discoloration of [[Tongue - Anatomy & Physiology|tongue]] due to having had FMD
 
**In these cases take scraping of retropharyngeal region, put scrapings in transport medium and send for testing
 
**In these cases take scraping of retropharyngeal region, put scrapings in transport medium and send for testing
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====Pathology====
 
====Pathology====
 
=====Gross=====
 
=====Gross=====
#Initially - hyperaemia of mucosa (e.g. catarrhal inflammation) then within 12 hours produces fluid filled vesicles on dorsum of [[Oral Cavity - Tongue - Anatomy & Physiology|tongue]], may be other places
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#Initially - hyperaemia of mucosa (e.g. catarrhal inflammation) then within 12 hours produces fluid filled vesicles on dorsum of [[Tongue - Anatomy & Physiology|tongue]], may be other places
 
#Small vesicle coalesce to produce big ones -i.e. Bullae
 
#Small vesicle coalesce to produce big ones -i.e. Bullae
 
#Very quickly rupture; epithelium appears dirty grey in colour because of necrosis - sloughed skin, very good for diagnosis
 
#Very quickly rupture; epithelium appears dirty grey in colour because of necrosis - sloughed skin, very good for diagnosis
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