Difference between revisions of "Lungs Developmental - Pathology"

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===Congenital atelectasis===
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===[[Pulmonary Congenital Atelectasis]]===
  
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*Incomplete expansion of the lung at birth (congenital) or collapse of previously air-filled lung ([[Lungs Ventilation - Pathology#Atelectasis (Collapse)|acquired]])
 
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*Failure of lung tissue to expand at birth
 
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*Ranges from total in stillborn animals to patchy areas in the case of weak neonates, showing more in the dependant lobes in recumbency
 
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*'''The neonatal respiratory syndrome'''
 
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**Best documented in foals but reported in other species
 
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**Also features extensive atelectasis
 
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**These animals are called 'barkers' due to the noise made during forced expiration
 
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*Gross pathology:
 
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**Red fleshy appearance to the affected part, depressed below the surface if there are adjacent normal aerated areas
 
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**Cut surface oozes blood, perhaps some froth in 'barkers'
 
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**Affected areas sink or are submerged in fixative
 
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*Micro pathology:
 
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**Close approximation of capillary walls
 
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**Little normal alveolar pattern
 
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**'Barkers' may have a proteinaceous fluid in alveoli with hyaline membranes in lower airways
 
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*Cause:
 
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**In weak neonates -inadequate respiratory effort or damage to the respiratory centres in the brain, aspiration of amniotic fluid or meconium
 
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**In 'barkers'- defective production of surfactant by the Type 2 alveolar epithelium
 
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*Foals that survive may have hypoxic damage to their brain, walk aimlessly and lack normal sense of fear - "wanderers"
 
  
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[[Category:Lungs - Developmental Pathology]]
 
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[[Category:Respiratory System - Developmental Pathology]]
 
  
 
===Congenital lobar emphysema===
 
===Congenital lobar emphysema===

Revision as of 16:54, 19 February 2011

Introduction

  • Congenital abnormalities of lungs are very rare, but most common in cattle
  • Most congenital abnormalities are incompatible with life


Accessory Lungs

Ciliary dyskinesia


Pulmonary Congenital Melanosis

Pulmonary Congenital Atelectasis

Congenital lobar emphysema


Pulmonary hypoplasia


Congenital alveolar dysplasia

  • Most common in dogs
  • Grossly:
    • Lungs retain fetal appearance and are poorly aerated
  • Histologically:
    • Uneven size and shape of alveoli, smaller number overall
    • Dilated blood vessels within extensive interstitial tissue
  • It is possible that in utero infection may contribute to this


Test yourself with the Lungs Pathology Flashcards

Lungs Pathology Flashcards

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