Difference between revisions of "Hyperthyroidism"
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| + | Seen most commonly in the cat. Elderly cats are affected with the average age of onset being 12-13 years. | ||
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| + | ''Clinical signs'': | ||
| + | *Weight loss despite polyphagia | ||
| + | *Increased activity, nervousness (approximately 10% will show apathy) | ||
| + | *Polyuria and polydipsia | ||
| + | *Heat intolerance, panting | ||
| + | *Tachycardia >240 bpm | ||
| + | *Poor coat, matted and unkempt | ||
| + | *Palpable thyroid mass often present | ||
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| + | Often see a [[Hypertrophic Cardiomyopathy|hypertrophic cardiomyopathy]] due to chronically increased heart rate and activity. | ||
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| + | [[Image:thyroid adenoma.jpg|right|thumb|125px|<small><center>'''Thyroid adenoma'''. Courtesy of T. Scase</center></small>]] | ||
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| + | ''Aetiopathogenesis'': | ||
| + | |||
| + | >98% are a functional adenoma of the thyroid gland and many will be palpable. | ||
| + | |||
| + | ''Treatment:'' | ||
| + | |||
| + | Surgical removal of the affected thyroid gland(s). If bilateral it is important to preserve at least one parathyroid gland to maintain calcium homeostasis. | ||
| + | |||
| + | Medical treatment: | ||
| + | *'''Carbamizole''': Interferes with thyroid hormone synthesis. | ||
| + | *'''Radioactive iodine''' therapy. Useful for intrathoracic thyroid nodules. | ||
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[[Category:To Do - Clinical]][[Category:Endocrine Diseases - Cat]] | [[Category:To Do - Clinical]][[Category:Endocrine Diseases - Cat]] | ||
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| + | [[Category:Thyroid Gland - Pathology]] | ||
Revision as of 13:58, 21 February 2011
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This article is still under construction. |
Seen most commonly in the cat. Elderly cats are affected with the average age of onset being 12-13 years.
Clinical signs:
- Weight loss despite polyphagia
- Increased activity, nervousness (approximately 10% will show apathy)
- Polyuria and polydipsia
- Heat intolerance, panting
- Tachycardia >240 bpm
- Poor coat, matted and unkempt
- Palpable thyroid mass often present
Often see a hypertrophic cardiomyopathy due to chronically increased heart rate and activity.
Aetiopathogenesis:
>98% are a functional adenoma of the thyroid gland and many will be palpable.
Treatment:
Surgical removal of the affected thyroid gland(s). If bilateral it is important to preserve at least one parathyroid gland to maintain calcium homeostasis.
Medical treatment:
- Carbamizole: Interferes with thyroid hormone synthesis.
- Radioactive iodine therapy. Useful for intrathoracic thyroid nodules.
Pathophysiology
Signalment
Presentation/Clinical Signs
- Weight loss
- Cardiovascular effects
- Palpable goitre
- Hyperactive
- Polyuria
- Polydipsia
Diagnosis
- T4 Assay
- T4 and TSH assay
Treatment
- Surgical - Thyroidectomy
- Medical - Thiamazole blocks synthesis of T3 and T4.
- Radioactive Iodine