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Hyperparathyroidism (view source)

Revision as of 14:45, 21 February 2011

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* There are two common forms of secondary hyperparathyroisism:

*# [[Parathyroid Glands - Pathology#Nutritional Hyperparathyroidism|'''Nutritional Hyperparathyroidism''']]

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*#* This includes [[~~Parathyroid Glands - Pathology#Metabolic Bone Disease|~~Metabolic Bone Disease]].

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*#* This includes [[Metabolic Bone Disease]].

*# [[Parathyroid Glands - Pathology#Renal Hyperparathyroidism|'''Renal Hyperparathyroidism''']]

* Both forms result in increased osteoclastic resorption of bone and deposition of fibro-osteoid matrix that fails to mineralise.

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** Osteoclastic resorption

** Fibrous replacement

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=====Metabolic Bone Disease=====

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=====[[Metabolic Bone Disease]]=====

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* Metabolic bone disease affects lizards in captivity, particularly young green iguanas

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* The condition is caused by:

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** Dietary deficiency of calcium and vitamin D

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*** For example, due to poor lighting (which diminishes viatmin D production).

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** Dietary excess of phosphorus

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** Certain toxicities

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** Diseases of the kidneys, [[Liver - Anatomy & Physiology|liver]] or parathyroid

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*** This aetiology is rare

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* Clinical signs include:

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** Lethargy

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** Inability to support weight

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** Rounded skull

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** Spontaneous fractures

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** Adult animals also show signs of [[Parathyroid Glands - Pathology#Hypocalcaemia|hypocalcaemia]]

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* The skeleton shows reduced density on radiography.

====Renal Hyperparathyroidism====

* Renal Hyerparathyroidism is mostly seen in the dog as an expression of chronic renal disease.

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