Difference between revisions of "Bullous Pemphigoid"
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m (Text replace - "Category:To Do - Blood" to "Category:To Do - BloodCategory:To Do - Clinical") |
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| + | '''Pathogenesis:''' [[Type II Hypersensitivity|Type II hypersensitivity]]? | ||
| − | + | *Dogs and horses | |
| + | *Involves oral cavity, mucocutaneous junctions, groin and axilla | ||
| + | *Subepidermal vesicles and bullae | ||
| + | *Antibodies bound to basement membrane | ||
| + | *Grossly: | ||
| + | **Similar to [[Pemphigus|Pemphigus vulgaris]] | ||
| + | *Microscopically: | ||
| + | **Bullae containing fibrin, [[Neutrophils|neutrophils]] or [[Eosinophils|eosinophils]] | ||
| + | **Basement membrane forms floor of bullae and roof is lined with basal cells | ||
| + | *Bullae may rupture -> ulcers | ||
| + | |||
| + | [[Category:Integumentary System - Autoimmune Reactions]] | ||
[[Category:Antibody Mediated Autoimmune Diseases]] | [[Category:Antibody Mediated Autoimmune Diseases]] | ||
[[Category:To Do - Blood]][[Category:To Do - Clinical]] | [[Category:To Do - Blood]][[Category:To Do - Clinical]] | ||
Revision as of 16:51, 22 February 2011
Pathogenesis: Type II hypersensitivity?
- Dogs and horses
- Involves oral cavity, mucocutaneous junctions, groin and axilla
- Subepidermal vesicles and bullae
- Antibodies bound to basement membrane
- Grossly:
- Similar to Pemphigus vulgaris
- Microscopically:
- Bullae containing fibrin, neutrophils or eosinophils
- Basement membrane forms floor of bullae and roof is lined with basal cells
- Bullae may rupture -> ulcers