Difference between revisions of "Muscle Neoplasia"
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(Created page with "===Primary neoplasia=== *Rare in domestic animals *'''Rhabdomyoma''' **Benign **''E.g.'' laryngeal in dogs **Grossly: ***Lobulated with no capsule **Histologically: ***Large gra...") |
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[[Category:Neoplasia]] | [[Category:Neoplasia]] | ||
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Latest revision as of 12:16, 7 March 2011
Primary neoplasia
- Rare in domestic animals
- Rhabdomyoma
- Benign
- E.g. laryngeal in dogs
- Grossly:
- Lobulated with no capsule
- Histologically:
- Large granular cells
- Positive staining for myoglobin and desmin (immunoperoxidase technique)
- Z - band material can be seen by electron microscopy
- Rhabdomyosarcoma
- Malignant
- Mainly in dogs
- Metastases via lymphatics or venous routes -> in lymph nodes, lungs, spleen, heart and eleswhere in skeletal muscle
- Grossly:
- Pink masses with no capsule
- Histologically:
- Very varied
- Cells with or without visible cross striations
- Most easily seen with iron haematoxylin
- Muscle tissue only contains myoglobin detected by immunoperoxidase method
Metastatic neoplasia
- Can occur to skeletal muscle (e.g. carcinoma, haemangiosarcoma)
- Infiltrative lipomas of dogs
- Mature adipocyte tumours
- Usually deep in subcutis or muscle
- Infiltate along fascial planes or into muscles
- Grossly:
- Soft muscles
- Yellow fat separating fasciculi
- Histologically:
- Well-differentiated adipose cells