Difference between revisions of "Duck Hepatitis Virus"
| Line 29: | Line 29: | ||
|sub-order = | |sub-order = | ||
|super-family = | |super-family = | ||
| − | |family = Picornaviridae | + | |family = [[:Category:Picornaviridae|Picornaviridae]] |
|sub-family = | |sub-family = | ||
| − | |genus = Enterovirus | + | |genus = [[:Category:Enteroviruses|Enterovirus]] |
|species = Duck Hepatitis Virus I and III | |species = Duck Hepatitis Virus I and III | ||
}} | }} | ||
| + | Also Known As: '''''Duck Viral Hepatitis''''' — '''''DVH''''' — '''''DH''''' | ||
| − | + | Caused By: '''''Duck Hepatitis Virus 1 and 3'' — ''DHV-I'' — ''DHV-III'' | |
| − | |||
| − | |||
==Introduction== | ==Introduction== | ||
| Line 45: | Line 44: | ||
The disease is '''notifiable''' to the World Organisation for Animal Health [http://www.oie.int/ (OIE)] | The disease is '''notifiable''' to the World Organisation for Animal Health [http://www.oie.int/ (OIE)] | ||
| + | |||
==Signalment== | ==Signalment== | ||
Ducks are the only species naturally affected. | Ducks are the only species naturally affected. | ||
| Line 57: | Line 57: | ||
DHV-I is present worldwide. | DHV-I is present worldwide. | ||
| − | DHV-II has only been reported in Norfolk, England <ref> Asplin, F. D. (1965) | + | DHV-II has only been reported in Norfolk, England <ref> Asplin, F. D. (1965) '''Duck hepatitis: vaccination against two serological types. '''''Vet. Rec.'', 77:1529-1530</ref> and no outbreaks have been recorded since the 1980’s. |
DHV-III has only occurred in the USA. | DHV-III has only occurred in the USA. | ||
The '''rat''' acts as a vector for Duck Hepatitis. | The '''rat''' acts as a vector for Duck Hepatitis. | ||
| + | |||
==Clinical Signs== | ==Clinical Signs== | ||
'''Sudden deaths, Opisthotonus, Paresis''', Paralysis, Enopthalmos. | '''Sudden deaths, Opisthotonus, Paresis''', Paralysis, Enopthalmos. | ||
| Line 68: | Line 69: | ||
Mortality rates are lower in DHV-II infections, reaching only 20%. | Mortality rates are lower in DHV-II infections, reaching only 20%. | ||
| + | |||
==Diagnosis== | ==Diagnosis== | ||
| − | On post-mortem examination, the '''[[Liver - Anatomy & Physiology| liver]]''' is '''enlarged''', appears '''greenish''' and displays distinct '''ecchymotic haemorrhages'''. | + | On post-mortem examination, the '''[[Avian Liver - Anatomy & Physiology|liver]]''' is '''enlarged''', appears '''greenish''' and displays distinct '''ecchymotic haemorrhages'''. |
| − | + | Splenic and [[Exotic Urinary System - Anatomy & Physiology#Avian||kidney]] swelling may also be evident. Cutaneous haemorrhage is often noted. | |
On histopathology, '''necrosis''' and inflammatory infiltrate are visible within hepatic cells. | On histopathology, '''necrosis''' and inflammatory infiltrate are visible within hepatic cells. | ||
| − | '''Innoculation''' from liver suspensions | + | '''Innoculation''' from liver suspensions can be used for confirmation of all DHVs. |
| − | '''Direct immunofluorescence''' can also confirm presence of DHV-I. | + | '''Direct [[immunofluorescence]]''' can also confirm presence of DHV-I. |
'''Virus Neutralisation (VN)''' serological tests can be used to monitor vaccination response and epidemiology. | '''Virus Neutralisation (VN)''' serological tests can be used to monitor vaccination response and epidemiology. | ||
| Line 83: | Line 85: | ||
==Treatment== | ==Treatment== | ||
No treatment is effective once infected. | No treatment is effective once infected. | ||
| + | |||
==Control== | ==Control== | ||
'''Vaccination''' is only commercially available against '''DHV-I'''. Immunisation involves two or three innoculations. Live, live attenuated and inactivated forms are available. | '''Vaccination''' is only commercially available against '''DHV-I'''. Immunisation involves two or three innoculations. Live, live attenuated and inactivated forms are available. | ||
| Line 88: | Line 91: | ||
DHV-I can be prevented by '''strict isolation''' in the first 4-5 weeks of life. | DHV-I can be prevented by '''strict isolation''' in the first 4-5 weeks of life. | ||
| − | The viruses are resistant to inactivation by heat, acid and some disinfectants. | + | The viruses are resistant to inactivation by heat, acid and some disinfectants. Only 5% phenol and formaldehyde are successful in inactivating the viruses. |
Duck Hepatitis is a '''Class B''' disease listed by the ''Office des International Epizooties'' and thus any ducks '''exported''' require an international veterinary '''certificate''' that they are from a DVH free establishment and are not exhibiting clinical signs of DH. Vaccination status must also be disclosed. | Duck Hepatitis is a '''Class B''' disease listed by the ''Office des International Epizooties'' and thus any ducks '''exported''' require an international veterinary '''certificate''' that they are from a DVH free establishment and are not exhibiting clinical signs of DH. Vaccination status must also be disclosed. | ||
| + | |||
{{Learning | {{Learning | ||
|literature search = [http://www.cabdirect.org/search.html?q=title%3A+%28Duck+Hepatitis+Virus%29/ DHV Publications] | |literature search = [http://www.cabdirect.org/search.html?q=title%3A+%28Duck+Hepatitis+Virus%29/ DHV Publications] | ||
| − | |||
|flashcards = [[Duck Hepatitis Virus Flashcards]] | |flashcards = [[Duck Hepatitis Virus Flashcards]] | ||
}} | }} | ||
| + | |||
==References== | ==References== | ||
| Line 103: | Line 107: | ||
| − | [[Category: | + | {{review}} |
| + | [[Category:CABI Expert Review]] | ||
| + | [[Category:Enteroviruses]] | ||
| + | [[Category:Avian Viruses]] | ||
| + | [[Category:Alimentary Diseases - Birds]] | ||
| + | [[Category:Neurological Diseases - Birds]] | ||
Revision as of 16:33, 16 June 2011
| DHV-II | |
|---|---|
| Order | RNA viruses |
| Family | Astroviridae |
| Genus | Astrovirus |
| Species | DHV-II |
| DHV-1 and DHV-III | |
|---|---|
| Order | RNA Viruses |
| Family | Picornaviridae |
| Genus | Enterovirus |
| Species | Duck Hepatitis Virus I and III |
Also Known As: Duck Viral Hepatitis — DVH — DH
Caused By: Duck Hepatitis Virus 1 and 3 — DHV-I — DHV-III
Introduction
Duck hepatitis is caused by the enteroviruses DHV-I and DHV-III.
It is a highly fatal disease of ducklings causing very high mortality, opisthotonus and hepatitis.
The disease is notifiable to the World Organisation for Animal Health (OIE)
Signalment
Ducks are the only species naturally affected.
DHV-I occurs only in young ducklings, usually <6 weeks of age and spreads rapidly within a flock. It is the most virulent of the three.
DHV-II is only reported in outdoor ducks on open fields.
Duck Hepatitis is not considered zoonotic.
Distribution
DHV-I is present worldwide.
DHV-II has only been reported in Norfolk, England [1] and no outbreaks have been recorded since the 1980’s.
DHV-III has only occurred in the USA.
The rat acts as a vector for Duck Hepatitis.
Clinical Signs
Sudden deaths, Opisthotonus, Paresis, Paralysis, Enopthalmos.
DHV-I infection is most virulent. Death usually occurs within 1-2 hours of clinical signs.
Mortality rates are lower in DHV-II infections, reaching only 20%.
Diagnosis
On post-mortem examination, the liver is enlarged, appears greenish and displays distinct ecchymotic haemorrhages.
Splenic and |kidney swelling may also be evident. Cutaneous haemorrhage is often noted.
On histopathology, necrosis and inflammatory infiltrate are visible within hepatic cells.
Innoculation from liver suspensions can be used for confirmation of all DHVs.
Direct immunofluorescence can also confirm presence of DHV-I.
Virus Neutralisation (VN) serological tests can be used to monitor vaccination response and epidemiology.
Treatment
No treatment is effective once infected.
Control
Vaccination is only commercially available against DHV-I. Immunisation involves two or three innoculations. Live, live attenuated and inactivated forms are available.
DHV-I can be prevented by strict isolation in the first 4-5 weeks of life.
The viruses are resistant to inactivation by heat, acid and some disinfectants. Only 5% phenol and formaldehyde are successful in inactivating the viruses.
Duck Hepatitis is a Class B disease listed by the Office des International Epizooties and thus any ducks exported require an international veterinary certificate that they are from a DVH free establishment and are not exhibiting clinical signs of DH. Vaccination status must also be disclosed.
| Duck Hepatitis Virus Learning Resources | |
|---|---|
 Test your knowledge using flashcard type questions |
Duck Hepatitis Virus Flashcards |
 Search for recent publications via CAB Abstract (CABI log in required) |
DHV Publications |
References
- ↑ Asplin, F. D. (1965) Duck hepatitis: vaccination against two serological types. Vet. Rec., 77:1529-1530
Animal Health & Production Compendium, Duck Hepatitis Virus datasheet, accessed 05/06/2011 @ http://www.cabi.org/ahpc/
 |
This article has been peer reviewed but is awaiting expert review. If you would like to help with this, please see more information about expert reviewing. |