Actinobacillus suis Flashcards

Question	Answer		Article
What type of bacteria is Actinobacillus suis?	A.suis is a beta-haemolytic Gram-negative bacterium.		Link to Article
What family does A.suis belong to?	Pasteurellaceae		Link to Article
How do the strains of A.suis differ?	Strains have differences in their: Lipopolysaccharides (LPS) known as 'O' antigens - variants O1,O2 and O3. Capsules (CPS) refered to as'K' antigen - variants K1, K2 and K3.		Link to Article
Which strains are most commonly isolated from clinical cases?	O1/K1 O2/K3		Link to Article
Which strain is the most virulent?	O2/K2		Link to Article
What species does A.suis mainly casue disease in?	Pigs (majority) Neonatal calfs Waterfowl Alpacas Horses		Link to Article
What toxins do A.suis encode for?	Similar toxins to apxI and apxII of A. pleuropneumoniae, but they are less virulent. Once an animal is infected with A.suis it can provide partial cross protection against A. pleuropneumoniae.		Link to Article
What are the wild hosts for A.suis?	Anatidae (ducks, geese and swans) Coypu A.suis can also affect domestic species including cattle, sheep, goats, alpacas, zebu, dogs, cats and tenuous links to equine disease have been recorded (A.suis-like microorganism rather than A.suis itself).		Link to Article
What diseases does A.suis cause?	Actinobacillosis in pigs Pneumonia and localised infections in neonatal calfs Airsaculitis in waterfowl Polyarthritis in alpacas Septicaemia, acute haemorrhagic pulmonary infarction and necrotizing pneumonia in horses (tenuous link)		Link to Article
What is the epidemiology of A.suis?	Spread via aerososl infection and invasion of the upper respiratory tract Haematogenously spread via infected emboli, adhering to the endothelium of blood vessels or becoming trapped in smaller vessels Colonise piglets in the first three weeks of life - not all become infected, some may be carriers		Link to Article
What is the name of the polysaccharide that it present in A.suis and fungal and lichen cell walls?	Pustulan		Link to Article

Further links

Actinobacillosis - Pig Flashcards

Actinobacillosis - Pig