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==Introduction==
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Seborrhea is characterised by a defect in keratinisation or cornification. This results in increased scale formation, a greasy skin and hair coat and often secondary inflammation and infection.
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*Epidermal growth or differentiation disorder
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There are large amounts of free fatty acids and cholesterol and decreased amounts of diester waxes in surface lipids which lead bacterial populations to become pathogenic [[:Category:Staphylococcus species|coagulase positive staphylococci]]
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===Seborrheic disease complex===
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It is a chronic disease affecting mainly dogs, but also sometimes cats and horses.
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===Primary idiopathic seborrhea===
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This is a common inherited skin disorder seen most frequently in Cocker Spaniels. Basal epidermal cells in affected dogs undergo accelerated cellular proliferation and turnover.
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There is an increase in the number of actively dividing basal cells, a shortened cell cycle, and a decreased transit time to the stratum corneum (7-8 days compared with 21-23 days). Hair follicles and sebaceous glands are also affected.
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*Abnormal cornification or function of sebaceous glands
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*Large amounts of free fatty acids and cholesterol
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*Decreased amounts of diester waxes in surface lipids
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*Bacterial population changes to pathogenic [[:Category:Staphylococcus species|coagulase positive staphylococci]]
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*Chronic disease affecting mainly dogs, sometimes cats and horses
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*Dry form - white to grey scales
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*Greasy form - scaly, excess brown to yellow lipids sticking to skin and hair
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===Primary idiopathic seborrhea===
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*Abnormal cornification
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*Epidermal turnover reduced to about 2/3 of normal
   
*Microscopically:  
 
*Microscopically:  
 
**Hyperkeratosis distending follicular ostia causing papillary appearance
 
**Hyperkeratosis distending follicular ostia causing papillary appearance
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**Lesions relevant to the other disease
 
**Lesions relevant to the other disease
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[[Category:To Do - Helen]]
    
[[Category:Integumentary System - Pathology]]
 
[[Category:Integumentary System - Pathology]]
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