Difference between revisions of "Aldosterone"
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| − | + | ==Overview== | |
| + | |||
| + | * Steroid hormone | ||
| + | * Secreted from the zona glomerulosa of the adrenal cortex of the adrenal gland | ||
| + | * Mineralocorticoid | ||
| + | * Most important regulator of plasma pottassium | ||
| + | * Stimulated directly by increased plasma pottassium | ||
| + | * Also stimulated as part of the [[Renin-Angiotensin-Aldosterone System (RAAS) - Anatomy & Physiology | Renin-Angiotensin-Aldosterone System (RAAS)]] | ||
| + | |||
| + | |||
| + | ==Action== | ||
| + | |||
| + | * Works by altering gene transcription | ||
| + | ** Affects ATP levels | ||
| + | |||
| + | ===Sodium=== | ||
| + | |||
| + | * Affects sodium entry and transport | ||
| + | * Increases sodium re-uptake to a small degree in distal convoluted tubule | ||
| + | |||
| + | |||
| + | ===Pottassium and Hydrogen=== | ||
| + | |||
| + | * Causes pottassium and hydrogen secretion | ||
| + | ** Pottassium via apical leak channels | ||
| + | ** Hydrogen by proton secretory proteins | ||
Revision as of 17:13, 2 July 2008
Overview
- Steroid hormone
- Secreted from the zona glomerulosa of the adrenal cortex of the adrenal gland
- Mineralocorticoid
- Most important regulator of plasma pottassium
- Stimulated directly by increased plasma pottassium
- Also stimulated as part of the Renin-Angiotensin-Aldosterone System (RAAS)
Action
- Works by altering gene transcription
- Affects ATP levels
Sodium
- Affects sodium entry and transport
- Increases sodium re-uptake to a small degree in distal convoluted tubule
Pottassium and Hydrogen
- Causes pottassium and hydrogen secretion
- Pottassium via apical leak channels
- Hydrogen by proton secretory proteins