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Sexual Differentiation - Anatomy & Physiology (view source)

Revision as of 08:38, 8 July 2008

1,523 bytes removed , 08:38, 8 July 2008

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* At this stage it is not possible to discriminate between male and female gonads.

* Y chromosomal determination of gonadal sex is only visible when primordial germ cell colonisation is complete.

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[[Image:Sexual Differentiation primordial germ cell migration a.jpg|right|thumb|250px|<center> Schematic showing Early Sexual Differentiation. (Courtesy of Pathways to Pregnancy and Parturition, Senger)</center>]]

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* '''Between cords''', the loose mesenchyme undergoes '''vascularisation''' and develops as '''stromal tissue'''.

* Within the stromal tissue, cells condense into clusters to form specialized endocrine units - the interstitial '''Leydig Cells'''

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[[Image:Sexual Differentiation early male a.jpg|right|thumb|250px|<center> Schematic showing Early Sexual Differentiation in the Male. (Courtesy of Pathways to Pregnancy and Parturition, Senger)</center>]]

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[[Image:Sexual Differentiation early male b.jpg|right|thumb|250px|<center> Schematic showing Early Sexual Differentiation in the Male. (Courtesy of Pathways to Pregnancy and Parturition, Senger)</center>]]

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** '''Mesenchymal cells''' give rise to '''Granulosa cells'''

** '''Germ cells''' give rise to '''Oocytes'''

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[[Image:Sexual Differentiation early female.jpg|right|thumb|250px|<center> Schematic showing Early Sexual Differentiation in the Female. (Courtesy of Pathways to Pregnancy and Parturition, Senger)</center>]]

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** Cranial Vagina

* Normal Ovarian activity is NOT essential for the development of normal female internal genetalia.

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[[Image:Sexual Differentiation internal genitalia.jpg|right|thumb|250px|<center> Schematic showing Development of Internal Genitalia. Copyright RVC 2008 (Courtesy of Proff.R.Abayesekara (RVC))</center>]]

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* Failure of proper endocrine communication between the gonads, internal and external genitalia can lead to '''dissociation''' of gonadal and genital sex.

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[[Image:Sexual Differentiation external genitalia.jpg|right|thumb|250px|<center> Schematic showing Development of External Genitalia. Copyright RVC 2008 (Courtesy of Proff.R.Abayesekara (RVC))</center>]]

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== Sexual Differentiation of the Brain ==

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