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Preparation and Examination of Blood Smear (view source)

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In severe toxaemia, neutrophils may show cytoplasmic vacuolation due to degranulation of lysosomes during disturbed maturation.

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'''<u>Hypersegmented neutrophil.</u>''' There are more than 5 nuclear lobes. Found in dogs on corticosteroid therapy (which prolongs the half life of the neutrophil) and may be associated with uraemia. Also seen in Poodles with familial macrocytosis.

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'''<u>Hypersegmented neutrophil.</u>''' There are more than 5 nuclear lobes. Found in dogs on corticosteroid therapy (which prolongs the half life of the neutrophil) and may be associated with uraemia. Also seen in Poodles with familial macrocytosis. <gallery widths="300">

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File:NWLLabfacts 19.jpg|'''Hypersegmented neutrophil''' ©NationWide Laboratories 2017

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