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== Introduction ==
 
== Introduction ==
 
Primary hypoadrenocorticism results when destruction of 90% of both the adrenal cortices leads to a clinical deficiency of all adrenal cortical hormones. The ACTH stimulation test is used to confirm a diagnosis. It is also useful to measure the Na:K ratio as evidence for mineralocorticoid deficiency but a low ratio is not seen in all cases of primary hypoadrenocorticism at initial presentation. Animals with secondary hypoadrenocorticism (deficient pituitary production of ACTH) are not expected to have electrolyte disturbances.
 
Primary hypoadrenocorticism results when destruction of 90% of both the adrenal cortices leads to a clinical deficiency of all adrenal cortical hormones. The ACTH stimulation test is used to confirm a diagnosis. It is also useful to measure the Na:K ratio as evidence for mineralocorticoid deficiency but a low ratio is not seen in all cases of primary hypoadrenocorticism at initial presentation. Animals with secondary hypoadrenocorticism (deficient pituitary production of ACTH) are not expected to have electrolyte disturbances.
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== Authors & References ==
 
== Authors & References ==
 
[[NationWide Laboratories]]
 
[[NationWide Laboratories]]
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[[Category:Investigation of canine and feline disease]]