Difference between revisions of "Rhodococcus equi"
Jump to navigation
Jump to search
| Line 1: | Line 1: | ||
<big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big> | <big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big> | ||
<big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big> | <big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big> | ||
| − | |||
| − | |||
| − | |||
===Overview=== | ===Overview=== | ||
| Line 10: | Line 7: | ||
*Found in soil and intestinal tract of animals | *Found in soil and intestinal tract of animals | ||
*Replicates at warm temperatures in soils contaminated by faeces of herbivores | *Replicates at warm temperatures in soils contaminated by faeces of herbivores | ||
| − | *Opportunistic respiratory pathogen of foals under 6 months causing suppurative | + | *Opportunistic respiratory pathogen of foals under 6 months causing suppurative [Bacterial infections#Rhodococcus equi|bronchoneumonia]] |
| Line 36: | Line 33: | ||
===Clinical infections=== | ===Clinical infections=== | ||
| − | * | + | *[[Bacterial infections#Rhodococcus equi|bronchoneumonia]] and lung abscessation in foals less than 4 months |
*Acute disease in 1 month-old foals: acute fever, anorexia, bronchopneumonia | *Acute disease in 1 month-old foals: acute fever, anorexia, bronchopneumonia | ||
*Insidious disease in 2-4 month-old foals with coughing, dyspnoea, weight loss, exercise intolerance, loud, moist rales on lung auscultation | *Insidious disease in 2-4 month-old foals with coughing, dyspnoea, weight loss, exercise intolerance, loud, moist rales on lung auscultation | ||
*Occasionally diarrhoea | *Occasionally diarrhoea | ||
| − | *Granulomatous ulcerative enterocolitis | + | *Granulomatous ulcerative enterocolitis, mesenteric lymphadenitis and [[Peritoneal cavity - inflammatory#Peritonitis|peritonitis]] in some foals following ingestion of contaminated sputum |
*Foals over 6 months refractory to pulmonary infection | *Foals over 6 months refractory to pulmonary infection | ||
*Superficial abscesses in horses over 6 months | *Superficial abscesses in horses over 6 months | ||
Revision as of 11:55, 20 July 2008
Overview
- Gram-positive aerobic saprophyte found worldwide
- Found in soil and intestinal tract of animals
- Replicates at warm temperatures in soils contaminated by faeces of herbivores
- Opportunistic respiratory pathogen of foals under 6 months causing suppurative [Bacterial infections#Rhodococcus equi|bronchoneumonia]]
Characteristics
- Grows on non-enriched media
- Salmon-pink mucoid colonies due to capsule and pigment production
- No haemolysis on blood agar
- Aerobic, non-motile
- CAMP test-positive
- Catalase positive, oxidase negative, weakly acid-fast
- Found as cocci and rods
- Intracellular pathogen
Pathogenesis and pathogenicity
- Organism present in faeces or healthy foals as well as adult horses
- Pastures can become heavily contaminated, leading to outbreaks
- Transmission via inhalation of dust contaminated with R. equi
- Virulence associated with specific surface antigens encoded by a large plasmid
- Capsular polysaccharide and mycolic acids in cell wall prevent phagocytosis
Clinical infections
- bronchoneumonia and lung abscessation in foals less than 4 months
- Acute disease in 1 month-old foals: acute fever, anorexia, bronchopneumonia
- Insidious disease in 2-4 month-old foals with coughing, dyspnoea, weight loss, exercise intolerance, loud, moist rales on lung auscultation
- Occasionally diarrhoea
- Granulomatous ulcerative enterocolitis, mesenteric lymphadenitis and peritonitis in some foals following ingestion of contaminated sputum
- Foals over 6 months refractory to pulmonary infection
- Superficial abscesses in horses over 6 months
- Occasional infections in pigs and cattle, causing cervical lymphadenopathy
- Subcutaneous abscesses and mediastinal granulomas in cats
- Pneumonia in HIV patients
Diagnosis
- History of disease on the farm, age of foals affected and clinical signs
- Auscultation and rediography of thorax confirms pulmonary disease