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Major Histocompatability Complexes (view source)
Revision as of 15:34, 28 August 2008
, 15:34, 28 August 2008→Presentation Pathway
===Presentation Pathway===
===Presentation Pathway===
*MHC I presents '''endogenous''' (that is, intracellular) peptides
*Viral proteins are broken down to peptides by the proteasome and transferred to the endoplasmic reticulum via TAP (Transporters associated with Antigen Processing) molecules
*Viral proteins are broken down to peptides by the proteasome and transferred to the endoplasmic reticulum via TAP (Transporters associated with Antigen Processing) molecules
*In the ER peptides are processed with empty MHC I molecules and exported to the cell surface for presentation
*In the ER peptides are processed with empty MHC I molecules and exported to the cell surface for presentation