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*Large, enveloped, negative-sense RNA virus  
 
*Large, enveloped, negative-sense RNA virus  
 
*'''Bullet-shaped''' with short glycoprotein spikes
 
*'''Bullet-shaped''' with short glycoprotein spikes
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 +
=Types and Subtypes=
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Two Genera:
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#Lyssaviruses: 7 genotypes
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##'''Genotype 1''' is '''classical rabies'''
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##Genotypes 2-7 more limited in distribution
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##Genotype 4 infects '''insectivorous bats'''
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#Vesiculoviruses are all '''exotic''' to the UK:
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##Vesicular Stomatitis Virus
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##Ephemeral Fever
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##Fish Rhabdoviruses, such as viral hemorrhagic syndrome and infectious haematopoetic necrosis virus
    
=Virulence and Pathogenesis=
 
=Virulence and Pathogenesis=
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*Rabies is a '''NOTIFIABLE''' zoonosis
 
*Rabies is a '''NOTIFIABLE''' zoonosis
 
*Rabies is found worldwide, though currently considered exotic to the UK and Australia
 
*Rabies is found worldwide, though currently considered exotic to the UK and Australia
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Host Range:
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*All mammals are susceptible
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**Very susceptible: foxes, jackals, wolves
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**Susceptible (10,000x virus necessary to infect): cats, rodents, bats, skunks, cattle, mongooses
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**Moderately susceptible (100,000x virus necessary to infect): dogs, sheep, goats, horses, primates
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*Isolates can show to some species specificity in their reservoir host
 
*Reservoir species by region:
 
*Reservoir species by region:
 
{| style="width:60%; height:200px" border="1" align=center
 
{| style="width:60%; height:200px" border="1" align=center
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*Immune recovered animals are rare, but are not shown to be infections
 
*Immune recovered animals are rare, but are not shown to be infections
   −
=Types and Subtypes=
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=Diagnosis=
Two Genera:
  −
#Lyssaviruses: 7 genotypes
  −
##'''Genotype 1''' is '''classical rabies'''
  −
##Genotypes 2-7 more limited in distribution
  −
##Genotype 4 infects '''insectivorous bats'''
  −
#Vesiculoviruses are all '''exotic''' to the UK:
  −
##Vesicular Stomatitis Virus
  −
##Ephemeral Fever
  −
##Fish Rhabdoviruses, such as viral hemorrhagic syndrome and infectious haematopoetic necrosis virus
     −
=Rhabdoviridae by Species=
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Host Range:
  −
*All mammals are susceptible
  −
**Very susceptible: foxes, jackals, wolves
  −
**Susceptible (10,000x virus necessary to infect): cats, rodents, bats, skunks, cattle, mongooses
  −
**Moderately susceptible (100,000x virus necessary to infect): dogs, sheep, goats, horses, primates
  −
*Isolates can show to some species specificity in their reservoir host
      
=Rabies Control=
 
=Rabies Control=
 
*Antigenicity allows a single antigenic type to vaccinate
 
*Antigenicity allows a single antigenic type to vaccinate
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