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Retroviridae
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Revision as of 20:14, 20 October 2008
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20:14, 20 October 2008
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**''env'': encodes envelope spikes, and can be used in diagnosis and subunit vaccines
**''env'': encodes envelope spikes, and can be used in diagnosis and subunit vaccines
*Both ends of genome show a promoter (LTR: long terminal repeat)
*Both ends of genome show a promoter (LTR: long terminal repeat)
+
+
=Antigenicity=
+
*Group-specific antigens (gag's) are shared by all isolates of each virus
+
**This can be exploited by diagnostic tests
+
*Lentiviruses show variation by mutation, making vaccination difficult
=Virulence and Pathogenesis=
=Virulence and Pathogenesis=
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#*Jembrana of Bali cattle
#*Jembrana of Bali cattle
#*Human Immunodeficiency Virus (HIV)
#*Human Immunodeficiency Virus (HIV)
−
−
=Antigenicity=
−
*Group-specific antigens (gag's) are shared by all isolates of each virus
−
**This can be exploited by diagnostic tests
−
*Lentiviruses show variation by mutation, making vaccination difficult
Bepocock
1,351
edits