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{{toplink
 
{{toplink
|backcolour = FFE4E1
   
|linkpage =Adaptive Immune System - WikiBlood
 
|linkpage =Adaptive Immune System - WikiBlood
 
|linktext =ADAPTIVE IMMUNE SYSTEM
 
|linktext =ADAPTIVE IMMUNE SYSTEM
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|pagetype =Blood
 
|pagetype =Blood
 
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===Actions and Tools of the Adaptive Immune System===
==<font color="purple">Actions and Tools of the Adaptive Immune System</font>==
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<FlashCard questions="6">
{| border="3" cellpadding="8"
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|q1=Complete the sentence:
!width="400"|'''Question'''
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<p>T cell receptors recognise ??? fragments on the cell surface. B cell receptors recognise ??? in the ??? fluid.</p>
!width="400"|'''Answer'''
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|a1=
!width="150"|'''Article'''
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*antigen
|-
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*whole antigen
|<big>'''Complete the sentence'''
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*extracellular
||<big>T cell receptors recognise <font color="white">'''''antigen fragments'''''</font> on the cell surface. B cell receptors recognise <font color="white">'''''whole antigen'''''</font> in the <font color="white">'''''extracellular fluid'''''</font>  
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|l1=Adaptive Immune System - WikiBlood#Antigen Recognition
||[[Adaptive Immune System - WikiBlood#Antigen Recognition|<span title="Answer article">Link to Answer Article</span>]]
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|q2=Dendritic cells and macrophages are types of which kind of cells?
|-
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|a2=Antigen presenting cells (APCs)
|<big>'''Dendritic cells and macrophages are types of which kind of cells?'''
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|l2=Adaptive Immune System - WikiBlood#Antigen Recognition
||<font color="white"> <big>
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|q3=What can CD3+ T cells differentiate into?
*'''''Antigen presenting cells (APCs)'''''
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|a3=
||[[Adaptive Immune System - WikiBlood#Antigen Recognition|<span title="Answer article">Link to Answer Article</span>]]
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*CD4+ Helper T cells
|-
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*CD8+ Cytotoxic T cells
|<big>'''What can CD3+ T cells differentiate into?'''
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|l3=Adaptive Immune System - WikiBlood#Cellular response: Proliferation and Differentiation
||<font color="white"> <big>
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|q4=What is the main function of T helper I cells?
*'''''CD4+ Helper T cells'''''
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|a4=Enhancing the macrophage response
*'''''CD8+ Cytotoxic T cells
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|l4=Adaptive Immune System - WikiBlood#Cellular response: Proliferation and Differentiation
||[[Adaptive Immune System - WikiBlood#Cellular response: Proliferation and Differentiation|<span title="Answer article">Link to Answer Article</span>]]
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|q5=What is the main function of T helper II cells?
|-
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|a5=Enhancing the B cell antibody production
|<big>'''What is the main function of T helper I cells?'''
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|l5=Adaptive Immune System - WikiBlood#Cellular response: Proliferation and Differentiation
||<font color="white"> <big>
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|q6=Name 3 types of antigen binding molecules
*'''''Enhancing the macrophage response'''''
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|a6=
||[[Adaptive Immune System - WikiBlood#Cellular response: Proliferation and Differentiation|<span title="Answer article">Link to Answer Article</span>]]
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*Immunolglobulins
|-
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*T cell receptors (TCRs)
|<big>'''What is the main function of T helper II cells?'''
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*Natural Killer cells (NK cells)
||<font color="white"> <big>
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|l6=Adaptive Immune System - WikiBlood#Antigen Binding Molecules
*'''''Enhancing the B cell antibody production'''''
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</FlashCard>
||[[Adaptive Immune System - WikiBlood#Cellular response: Proliferation and Differentiation|<span title="Answer article">Link to Answer Article</span>]]
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===Adaptive Immunity to Viruses===
|-
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<FlashCard questions="3">
|<big>'''Name 3 types of antigen binding molecules'''
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|q1=Which humoral factors are used against viruses in the adaptive response?
||<font color="white"> <big>
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|a1=
*'''''Immunolglobulins'''''
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*Production of neutralising antibody
*'''''T cell receptors (TCRs)'''''
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*Antibody-dependent cell mediated cytotoxicity (ADCC)
*'''''Natural Killer cells (NK cells)'''''
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|l1=Adaptive Immune System - WikiBlood#Adaptive Immunity to Viruses
||[[Adaptive Immune System - WikiBlood#Antigen Binding Molecules|<span title="Answer article">Link to Answer Article</span>]]
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|q2=What is the cell mediated adaptive response against viruses?
|}
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|a2=CD8+ T-cell mediated killing of virus infected cells
<br>
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|l2=Adaptive Immune System - WikiBlood#Adaptive Immunity to Viruses
<br>
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|q3=How are viral infected cells killed by apoptosis?
==<font color="purple">Adaptive Immunity to Viruses</font>==
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|a3=
{| border="3" cellpadding="8"
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*Perforin and granzymes released to activate the caspase cascade
!width="400"|'''Question'''
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*Fas-ligand triggers the Fas-mediated apoptosis pathway
!width="400"|'''Answer'''
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*Cytotoxic cytokines act on TNF receptors to induce programmed cell death
!width="150"|'''Article'''
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|l3=Adaptive Immune System - WikiBlood#Adaptive Immunity to Viruses
|-
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</FlashCard>
|<big>'''Which humoral factors are used against viruses in the adaptive response?'''
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===Adaptive Immunity to Bacteria===
||<font color="white"> <big>
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<FlashCard questions="4">
*'''''Production of neutralising antibody'''''
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|q1=What is the humoral response to bacterial infection?
*'''''Antibody-dependent cell mediated cytotoxicity (ADCC)'''''
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|a1=
||[[Adaptive Immune System - WikiBlood#Adaptive Immunity to Viruses|<span title="Answer article">Link to Answer Article</span>]]
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*Complement activation of the classical pathway
|-
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*Production of IgM and IgG
|<big>'''What is the cell mediated adaptive response against viruses?'''
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|l1=Adaptive Immune System - WikiBlood#Adaptive Immunity to Bacteria
||<font color="white"> <big>
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|q2=What is the cell-mediated response to bacterial infection?
*'''''CD8+ T-cell mediated killing of virus infected cells'''''
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|a2=
||[[Adaptive Immune System - WikiBlood#Adaptive Immunity to Viruses|<span title="Answer article">Link to Answer Article</span>]]
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*Help for macrophages
|-
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*Production of IgG
|<big>'''How are viral infected cells killed by apoptosis?'''
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*T helper type I cell help
||<font color="white"> <big>
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|l2=Adaptive Immune System - WikiBlood#Adaptive Immunity to Bacteria
*'''''Perforin and granzymes released to activate the caspase cascade'''''
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|q3=What is the response to an extracellular bacterial infection?
*'''''Fas-ligand triggers the Fas-mediated apoptosis pathway'''''
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|a3=Complement and phagocytosis
*'''''Cytotoxic cytokines act on TNF receptors to induce programmed cell death'''''
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*Production of IgM
||[[Adaptive Immune System - WikiBlood#Adaptive Immunity to Viruses|<span title="Answer article">Link to Answer Article</span>]]
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*T helper type II and B cell production
|}
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*Class switching of IgM to IgG
<br>
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|l3=Adaptive Immune System - WikiBlood#Adaptive Immunity to Bacteria
<br>
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|q4=What is the response to a vesicular bacterial infection?
==<font color="purple">Adaptive Immunity to Bacteria</font>==
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|a4=
{| border="3" cellpadding="8"
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*IL-12 released from an infected macrophage
!width="400"|'''Question'''
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*T helper type I cells stimulated
!width="400"|'''Answer'''
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*IFN-γ released triggering the macrophages to destroy the bacteria
!width="150"|'''Article'''
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|l4=Adaptive Immune System - WikiBlood#Adaptive Immunity to Bacteria
|-
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</FlashCard>
|<big>'''What is the humoral response to bacterial infection?'''
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===Adaptive Immunity to Parasites===
||<font color="white"> <big>
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<FlashCard questions="1">
*'''''Complement activation of the classical pathway'''''
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|q1=What is the humoral response to a parasitic infection?
*'''''Production of IgM and IgG'''''
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|a1=Production of IgE
||[[Adaptive Immune System - WikiBlood#Adaptive Immunity to Bacteria|<span title="Answer article">Link to Answer Article</span>]]
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|l1=Adaptive Immune System - WikiBlood#Adaptive Immunity to Parasites
|-
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</FlashCard>
|<big>'''What is the cell-mediated response to bacterial infection?'''
  −
||<font color="white"> <big>
  −
*'''''Help for macrophages'''''
  −
*'''''Production of IgG'''''
  −
*'''''T helper type I cell help'''''
  −
||[[Adaptive Immune System - WikiBlood#Adaptive Immunity to Bacteria|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''What is the response to an extracellular bacterial infection?'''
  −
||<font color="white"> <big>
  −
*'''''Complement and phagocytosis'''''
  −
*'''''Production of IgM'''''
  −
*'''''T helper type II and B cell production'''''
  −
*'''''Class switching of IgM to IgG'''''
  −
||[[Adaptive Immune System - WikiBlood#Adaptive Immunity to Bacteria|<span title="Answer article">Link to Answer Article</span>]]
  −
|-
  −
|<big>'''What is the response to a vesicular bacterial infection?'''
  −
||<font color="white"> <big>
  −
*'''''IL-12 released from an infected macrophage'''''
  −
*'''''T helper type I cells stimulated'''''
  −
*'''''IFN-γ released triggering the macrophages to destroy the bacteria'''''
  −
||[[Adaptive Immune System - WikiBlood#Adaptive Immunity to Bacteria|<span title="Answer article">Link to Answer Article</span>]]
  −
|}
  −
<br>
  −
<br>
  −
==<font color="purple">Adaptive Immunity to Parasites</font>==
  −
{| border="3" cellpadding="8"
  −
!width="400"|'''Question'''
  −
!width="400"|'''Answer'''
  −
!width="150"|'''Article'''
  −
|-
  −
|<big>'''What is the humoral response to a parasitic infection?'''
  −
||<font color="white"> <big>
  −
*'''''Production of IgE'''''
  −
||[[Adaptive Immune System - WikiBlood#Adaptive Immunity to Parasites|<span title="Answer article">Link to Answer Article</span>]]
  −
|}
  −
<br>
  −
<br>
  −
<big><center>[[Adaptive Immune System - WikiBlood|'''BACK TO THE ADAPTIVE IMMUNE SYSTEM''']]</center></big>
  −
<big><center>[[Flash Cards - WikiBlood|'''BACK TO WIKIBLOOD FLASHCARDS''']]</center></big>