Difference between revisions of "Category:Campylobacter species"

Revision as of 21:32, 10 May 2010

Live on mucosa of intestinal and genital tract and can be commensals or pathogens
Enteric species cause disease in humans
Other species cause infertility and abortion in cattle and sheep
Excreted in faeces of birds, (C. jejuni and C. lari) as well as pigs contaminating water and food supplies
C. fetus restricted to bovine prepucial mucosa

Curved, Gram negative rods
Polar flagellum aids motility
Daughter cells remain joined giving gull-wing or spiral appearance
Microaerophilic
Sensitive to drying
Thermophilic species - C. jejuni, C. coli
Non-thermophilic species e.g. C. fetus
Grow on enriched selective media e.g. Skirrow agar in 1-10% carbon dioxide and 5-10% oxygen tension
C. jejuni requires increased temperatures for growth
Many grow on MacConkey
Oxidase positive, non-fermentative
C. fetus subspecies venerealis and subspecies fetus have small, round, smooth, translucent colonies
C. jejuni has small, flat, grey colonies with watery appearance
Smears stained with dilute carbol fuschin for 4 minutes

C. fetus subspecies fetus and subspecies venerealis possess a microcapsule (S layer) which resists phagocytosis and serum-mediated destruction and enhances survival in the genital tract
Antigens of S layer undergoes antigenic shifts in C. fetus subspecies venerealis, allowing persistence in the host
C. jejuni attaches and invades host enterocytes and produces enterotoxin-like substances
Flagellae of C. jejuni required for colonisation

The following 5 pages are in this category, out of 5 total.

@@ Line 40: / Line 40: @@
+[[Campylobacter jejuni]]
-===[[Intestine Pathogens - Pathology#Campylobacter jejuni|''Campylobacter jejuni'']]===
-*Widespread on farms - hyperendemic
-*Carried as commensals in intestines of cattle, sheep, dogs, wild birds and especially chickens
-*Farm animals regularly exposed via faecal-oral route; maternal antibody protects while active immunity develops
-*Animals with little exposure are very susceptible, e.g. humans, pets
-*Most chicken carcasses contaminated, leading to food poisoning and enterocolitis in people from uncooked meat
-*Colonisation, attachment and invasion of colonic enterocytes; toxin production
-*Necrosis of colonic absorptive epithelial cells, erosion of mucosa, crypt abscesses, inflammatory infiltrate of [[Neutrophils - WikiBlood|neutrophils]] into mucosa causes colitis
-*Enteritis and diarrhoea in susceptible dogs; treatment with enrofloxacin
-*Causes abortion in ewes
-*Usually asymptomatic infections in chickens and turkeys, but occasional outbreaks of avian hepatitis occur with decreased egg production, loss of condition, haemorrhage and necrosis of liver; phase contrast microscopy demonstrates curved rods in bile; in-feed dihydrostreptomycin sulphate in outbreak
-*Implicated in [[Intestines Catarrhal Enteritis - Pathology#Undifferentiated Neonatal Calf Diarrhoea|undifferentiated neonatal calf diarrhoea]], a mixed viral enteritis in calves
 [[Category:Bacteria]][[Category:Gram_negative_bacteria]]