Difference between revisions of "Equine Infectious Anemia"
Jump to navigation
Jump to search
| Line 1: | Line 1: | ||
{{unfinished}} | {{unfinished}} | ||
| − | + | EIA | |
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| Line 39: | Line 32: | ||
*2 clear Coggins tests of all horses before movement allowed | *2 clear Coggins tests of all horses before movement allowed | ||
*Vector control: stabling, etc. | *Vector control: stabling, etc. | ||
| + | [[Category:Lentiviruses]][[Category:Horse]] | ||
Revision as of 12:14, 23 May 2010
 |
This article is still under construction. |
EIA
Pathogenesis
- Virus coats red blood cells and thrombocytes
- Type III Immune complex disease develops
- Non-neutralizing antibody and complement lyse RBC's, causing:
- Jaundice
- Vasculitis
- Hemorrhage
- Diarrhoea
- Loss of condition
- Oedema
- High mortality
Epidemiology
- Notifiable in UK but endemic in parts of the US
- Animals can be carriers for years despite being antibody-positive
- Transfer is mechanical via vectors:
- Mosquitoes transfer infected macrophages
- Also transferred via infected needles, semen and milk
- Infected horses have lifetime latent infection of macrophages with recurring bouts of virus when immunocompromised
Diagnosis
- Coggins test required for horse movement in the US:
- Serum antibody by immunodiffusion in infected horse spleen
Control
- Slaughter of infected animal
- 2 clear Coggins tests of all horses before movement allowed
- Vector control: stabling, etc.