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| | *May cause [[Bones Developmental - Pathology#Retention of elongated primary trabeculae|growth retardation lattice]] | | *May cause [[Bones Developmental - Pathology#Retention of elongated primary trabeculae|growth retardation lattice]] |
| | *May also trigger latent [[Toxoplasma|Toxoplasmosis]] due to suppressing effect on lymphoid tissue | | *May also trigger latent [[Toxoplasma|Toxoplasmosis]] due to suppressing effect on lymphoid tissue |
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| | + | ===Canine distemper=== |
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| | + | *Caused by a [[Paramyxoviridae#Canine Distemper Virus (CDV)|morbillivirus]] |
| | + | *[[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|Rhinitis]] |
| | + | *Although many organs can be affected by CDV, a relatively constant feature is the respiratory signs which occur in varying severity |
| | + | *A syndrome of catharral oculonasal discharge, [[Nasopharynx Inflammatory - Pathology#Infectious causes of pharyngitis|pharyngitis]] and [[Bronchi and Bronchioles Inflammatory - Pathology#Infectious causes of bronchitis or bronchiolitis|bronchitis]] is relatively common in the initial stages |
| | + | *Since one of the primary sites of action of this virus is lymphoid tissue, the resultant immunosuppression -> predisposition to secondary bacterial infection |
| | + | *May cause [[Lungs Inflammatory - Pathology#Interstitial pneumonia|interstitial pneumonia]] where [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|inclusions]] are found within alveolar macrophages |
| | + | *Gross pathology: |
| | + | **Oedematous lungs, diffuse interstitial pneumonia |
| | + | *Micro pathology: |
| | + | **Necrosis of pneumocytes, necrotising bronchiolitis, alveolar oedema, thickening of alveolar walls and type II pneumocyte hyperplasia |
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| | [[Category:Morbilliviruses]][[Category:Dog]] | | [[Category:Morbilliviruses]][[Category:Dog]] |
| | [[Category:To_Do_-_Viruses]] | | [[Category:To_Do_-_Viruses]] |